Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | GALR3 | O60755 | 1/20 | 0.54 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14093583 | 0.86 | PDE4D (0.59) | PDE4DLMNARAB9AHTTSMN1; SMN2 | |
| SCHEMBL6371454 | 0.84 | PDE4D (0.57) | PDE4DLMNARAB9AHTTSMN1; SMN2 | |
| SCHEMBL14093582 | 0.83 | PDE4D (0.56) | PDE4DLMNARAB9AHTTSMN1; SMN2 | |
| SCHEMBL14320162 | 0.83 | SLC6A2 (0.58) | PDE4DLMNARAB9AHTTSMN1; SMN2 | |
| SCHEMBL8969367 | 0.81 | PDE4D (0.54) | PDE4DLMNARAB9AHTTSMN1; SMN2 | |
| SCHEMBL6338588 | 0.80 | SIGMAR1 (0.62) | PDE4DLMNARAB9AHTTSMN1; SMN2 | |
| SCHEMBL5127182 | 0.79 | GAA (0.66) | PDE4DLMNARAB9AHTTSMN1; SMN2 | |
| SCHEMBL14470052 | 0.78 | POLB (0.67) | PDE4DLMNARAB9AHTTSMN1; SMN2 | |
| SCHEMBL29964126 | 0.78 | NPC1 (0.61) | PDE4DLMNARAB9AHTTSMN1; SMN2 | |
| SCHEMBL29212110 | 0.78 | NPC1 (0.61) | PDE4DLMNARAB9AHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5114949-A | Treating disorders associated with 5HT uptake | RHONE-POULENC SANTE (FR) | 1992-05-19 | — | — | US | disclosed |