Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 8/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5222189 | 0.92 | LMNA (0.54) | ALDH1A1LMNACA2GPR84 | |
| SCHEMBL4655341 | 0.86 | ALDH1A1 (0.52) | ALDH1A1LMNACA2TDP1CYP3A4 | |
| SCHEMBL1116216 | 0.76 | ALDH1A1 (0.59) | ALDH1A1LMNACA2TDP1CYP3A4 | |
| SCHEMBL20746322 | 0.76 | ALDH1A1 (0.59) | ALDH1A1LMNACA2TDP1CYP3A4 | |
| SCHEMBL9092266 | 0.76 | ALDH1A1 (0.59) | ALDH1A1LMNACA2TDP1CYP3A4 | |
| SCHEMBL6011969 | 0.76 | ALDH1A1 (0.59) | ALDH1A1LMNACA2TDP1CYP3A4 | |
| SCHEMBL6011884 | 0.76 | ALDH1A1 (0.59) | ALDH1A1LMNACA2TDP1CYP3A4 | |
| SCHEMBL20746352 | 0.76 | ALDH1A1 (0.59) | ALDH1A1LMNACA2TDP1CYP3A4 | |
| SCHEMBL3689153 | 0.76 | ALDH1A1 (0.59) | ALDH1A1LMNACA2TDP1CYP3A4 | |
| SCHEMBL14125873 | 0.76 | ALDH1A1 (0.59) | ALDH1A1LMNACA2TDP1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0162016-B1 | ADDITIVES FOR MATERIALS | CIBA-GEIGY AG (CH) | 1992-06-03 | — | — | EP | claimed |
| EP-0162016-A2 | Additives for materials | CIBA-GEIGY AG (CH) | 1985-11-21 | — | — | EP | claimed |