Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 11/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 10/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.44 |
| ▸ | MMP3 | P08254 | 2/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.39 |
| ▸ | ESRRB | O95718 | 1/20 | 0.35 |
| ▸ | ESRRA | P11474 | 1/20 | 0.35 |
| ▸ | USP7 | Q93009 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9636799 | 0.87 | AR (0.39) | ESR1ESR2ARESRRBESRRA | |
| SCHEMBL9635428 | 0.83 | HSD17B10 (0.41) | — | |
| SCHEMBL13756111 | 0.78 | FFAR1 (0.36) | AR | |
| SCHEMBL9635251 | 0.73 | ALDH1A1 (0.47) | — | |
| SCHEMBL13756110 | 0.72 | TSHR (0.42) | — | |
| SCHEMBL2785589 | 0.68 | AR (0.57) | ESR1ESR2ARMMP3HSD17B1 | |
| SCHEMBL5067426 | 0.68 | AR (0.57) | ESR1ESR2ARMMP3 | |
| SCHEMBL14675129 | 0.68 | ESR2 (0.38) | ESR1ESR2ARUSP7ALOX5 | |
| SCHEMBL1257364 | 0.68 | GABRA1 (0.52) | ESR1ESR2ARHSD17B1MEN1 | |
| SCHEMBL13263907 | 0.67 | AR (0.48) | ESR1ESR2ARMMP3HSD17B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0283326-B1 | LIQUID CRYSTAL COMPOUNDS WITH 4-(OPTICALLY ACTIVE ALKYL)-3-CYANOPHENYL GROUPS | Chisso Corporation (JP) | 1992-06-24 | — | — | EP | disclosed |
| US-4913838-A | LARGE SPONTANEOUS POLARIZATION VALUE | CHISSO CORPORATION (JP) | 1990-04-03 | — | — | US | disclosed |