Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | GBA1 | P04062 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | OXTR | P30559 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 2/20 | 0.37 |
| ▸ | ACLY | P53396 | 1/20 | 0.37 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.37 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9636847 | 0.80 | GBA1 (0.50) | SIGMAR1KCNH2GBA1KDM1AKDM1B | |
| SCHEMBL2247241 | 0.77 | SIGMAR1 (0.52) | SIGMAR1HTR1ANISCHOPRM1OPRL1 | |
| SCHEMBL716596 | 0.74 | SIGMAR1 (0.52) | SIGMAR1HTR1ANISCHOPRM1OPRL1 | |
| SCHEMBL13572973 | 0.74 | SIGMAR1 (0.52) | SIGMAR1HTR1ANISCHOPRM1OPRL1 | |
| SCHEMBL20864244 | 0.74 | SIGMAR1 (0.56) | SIGMAR1HTR1ANISCHOPRM1OPRL1 | |
| SCHEMBL8578251 | 0.74 | SIGMAR1 (0.52) | SIGMAR1HTR1ANISCHOPRM1OPRL1 | |
| SCHEMBL8354157 | 0.74 | SIGMAR1 (0.52) | SIGMAR1HTR1ANISCHOPRM1OPRL1 | |
| SCHEMBL13572976 | 0.74 | SIGMAR1 (0.52) | SIGMAR1HTR1ANISCHOPRM1OPRL1 | |
| Hydrochloric Acid SCHEMBL31621993 | 0.72 | SIGMAR1 (0.51) | SIGMAR1HTR1ANISCHOPRM1OPRL1 | |
| Hydrochloric Acid SCHEMBL29466506 | 0.72 | SIGMAR1 (0.51) | SIGMAR1HTR1ANISCHOPRM1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5114949-A | Treating disorders associated with 5HT uptake | RHONE-POULENC SANTE (FR) | 1992-05-19 | — | — | US | disclosed |