Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 5/20 | 0.44 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11231387 | 0.84 | GBA1 (0.50) | GBA1KDM1AKDM1BHTR2CSLC6A4 | |
| Hydrochloric Acid SCHEMBL11232679 | 0.82 | IDO1 (0.50) | GBA1KDM1AKDM1BHTR2CSLC6A4 | |
| SCHEMBL9635416 | 0.81 | MTNR1A (0.49) | GBA1KDM1AKDM1BHTR2CSLC6A4 | |
| SCHEMBL11232129 | 0.81 | NAMPT (0.49) | GBA1KDM1AKDM1BHTR2CSLC6A4 | |
| SCHEMBL9635403 | 0.80 | SIGMAR1 (0.47) | GBA1KDM1AKDM1BSIGMAR1KCNH2 | |
| SCHEMBL5435617 | 0.77 | ACHE (0.68) | SIGMAR1CYP19A1 | |
| SCHEMBL30861080 | 0.77 | ACHE (0.68) | SIGMAR1CYP19A1 | |
| SCHEMBL331996 | 0.75 | GBA1 (0.42) | GBA1 | |
| SCHEMBL11222695 | 0.73 | KDM1A (0.46) | GBA1KDM1AKDM1BHTR2CSLC6A4 | |
| SCHEMBL8243145 | 0.73 | BCHE (0.53) | HTR2CHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5114949-A | Treating disorders associated with 5HT uptake | RHONE-POULENC SANTE (FR) | 1992-05-19 | — | — | US | disclosed |