Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 2/20 | 0.43 |
| ▸ | GRM8 | O00222 | 2/20 | 0.43 |
| ▸ | GRM6 | O15303 | 2/20 | 0.43 |
| ▸ | GRM7 | Q14831 | 2/20 | 0.43 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.43 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.43 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.43 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.43 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.43 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.43 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.43 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.43 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.43 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.43 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.43 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10915178 | 0.78 | CYP2D6 (0.61) | GSRGRM8GRM6GRM7GRM4 | |
| SCHEMBL8531395 | 0.78 | CYP2D6 (0.61) | GSRGRM8GRM6GRM7GRM4 | |
| SCHEMBL8531394 | 0.78 | CYP2D6 (0.61) | GSRGRM8GRM6GRM7GRM4 | |
| SCHEMBL9635451 | 0.77 | BLM (0.59) | GSRGRM8GRM6GRM7GRM4 | |
| SCHEMBL9635455 | 0.77 | BLM (0.59) | GSRGRM8GRM6GRM7GRM4 | |
| Hydrochloric Acid SCHEMBL10963186 | 0.76 | CYP2D6 (0.59) | GSRGRM8GRM6GRM7GRM4 | |
| Hydrochloric Acid SCHEMBL10963195 | 0.76 | CYP2D6 (0.59) | GSRGRM8GRM6GRM7GRM4 | |
| Hydrochloric Acid SCHEMBL10963203 | 0.76 | CYP2D6 (0.59) | GSRGRM8GRM6GRM7GRM4 | |
| Bicarbonate SCHEMBL8532146 | 0.76 | GRIK1 (0.37) | GRIK1SLC1A3SLC1A2SLC1A1GRIK2 | |
| SCHEMBL602426 | 0.75 | GSR (0.68) | GSRGRM8GRM6GRM7GRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1027891-C | Process for the preparation of 5-substituted ornithine derivatives | MERRELL DOW PHARMA (US) | 1995-03-15 | — | — | CN | disclosed |
| EP-0326766-B1 | 5-SUBSTITUTED ORNITHINE DERIVATIVES | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-06-17 | — | — | EP | disclosed |
| US-4902719-A | ORNITHINE DEFICIENCY TREATMENT | MERRELL DOW PHARMACEUTICALS INC. (US) | 1990-02-20 | — | — | US | disclosed |
| CN-1037142-A | The 5-substituted ornithine derivatives | MERRELL DOW PHARMA (US) | 1989-11-15 | — | — | CN | disclosed |
| EP-0326766-A1 | 5-Substituted ornithine derivatives | MERRELL DOW PHARMACEUTICALS INC. (US) | 1989-08-09 | — | — | EP | disclosed |