Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | MAOB | P27338 | 4/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5073 | 0.82 | TDP1 (0.50) | ALDH1A1TDP1CYP3A4TSHRMAPT | |
| SCHEMBL9171098 | 0.81 | ALDH1A1 (0.44) | ALDH1A1TDP1CYP3A4TSHRMAPT | |
| Hydrochloric Acid SCHEMBL8756363 | 0.80 | TDP1 (0.48) | ALDH1A1TDP1CYP3A4TSHRMAPT | |
| Hydrochloric Acid SCHEMBL3785323 | 0.80 | TDP1 (0.48) | ALDH1A1TDP1CYP3A4TSHRMAPT | |
| SCHEMBL9476043 | 0.78 | ALDH1A1 (0.46) | ALDH1A1TDP1CYP3A4TSHRMAPT | |
| SCHEMBL2140301 | 0.78 | ALDH1A1 (0.46) | ALDH1A1TDP1CYP3A4TSHRMAPT | |
| SCHEMBL8812561 | 0.78 | ALDH1A1 (0.46) | ALDH1A1TDP1CYP3A4TSHRMAPT | |
| SCHEMBL12012136 | 0.78 | ALDH1A1 (0.48) | ALDH1A1TDP1CYP3A4TSHRMAPT | |
| SCHEMBL20505766 | 0.78 | ALDH1A1 (0.54) | ALDH1A1TDP1CYP3A4TSHRMAPT | |
| SCHEMBL9587435 | 0.78 | TDP1 (0.41) | ALDH1A1TDP1CYP3A4TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0278673-B1 | A BENZOYLUREA DERIVATIVE AND ITS PRODUCTION AND USE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1992-05-13 | — | — | EP | disclosed |
| EP-0278673-A2 | A benzoylurea derivative and its production and use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1988-08-17 | — | — | EP | disclosed |
| EP-0058424-B1 | PYRAZOLINE DERIVATIVES | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1985-09-18 | — | — | EP | disclosed |
| US-4464386-A | Insecticidal 3-difluoromethoxyphenyl-1-phenylcarbamoyl-2-pyrazolines | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1984-08-07 | — | — | US | disclosed |