Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.54 |
| ▸ | IDO1 | P14902 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.47 |
| ▸ | LDHA | P00338 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | STAT1 | P42224 | 1/20 | 0.45 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.43 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.43 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.43 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.43 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10844985 | 0.99 | ALOX5 (0.53) | ALOX5IDO1KDM4ELDHAEPHX2 | |
| SCHEMBL10961718 | 0.86 | ALDH1A1 (0.45) | ALOX5KDM4ELDHAEPHX2ALDH1A1 | |
| SCHEMBL9634856 | 0.86 | KDM4E (0.44) | ALOX5KDM4ELDHAEPHX2ALDH1A1 | |
| SCHEMBL9634555 | 0.84 | KDM4E (0.42) | ALOX5KDM4ELDHAEPHX2ALDH1A1 | |
| SCHEMBL10734279 | 0.83 | ALOX5 (0.47) | ALOX5IDO1KDM4EALDH1A1HPGD | |
| SCHEMBL7272011 | 0.83 | ALOX5 (0.51) | ALOX5KDM4ELDHAEPHX2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL10850991 | 0.82 | ALOX5 (0.50) | ALOX5KDM4ELDHAEPHX2ALDH1A1 | |
| SCHEMBL7279556 | 0.82 | NPC1 (0.52) | KDM4ELDHAEPHX2ALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL7271663 | 0.82 | ALOX5 (0.50) | ALOX5KDM4ELDHAEPHX2ALDH1A1 | |
| SCHEMBL9635805 | 0.81 | KDM4E (0.42) | ALOX5KDM4ELDHAEPHX2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5104881-A | 2-ARYLIMIDAZOPYRIDINES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-04-14 | — | — | US | disclosed |
| US-4616090-A | 2-arylimidazopyridines intermediates | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1986-10-07 | — | — | US | disclosed |
| EP-0072926-B1 | 2-ARYLIMIDAZOPYRIDINES | MERCK PATENT GmbH (DE) | 1986-09-24 | — | — | EP | disclosed |
| EP-0072926-A1 | 2-Arylimidazopyridines | MERCK PATENT GmbH (DE) | 1983-03-02 | — | — | EP | disclosed |