Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | TDO2 | P48775 | 1/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.36 |
| ▸ | MPI | P34949 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14690627 | 0.75 | ALDH1A1 (0.47) | ALDH1A1KDM4EMAPTPOLBSMN1; SMN2 | |
| SCHEMBL496927 | 0.75 | PDE4A (0.48) | ALDH1A1KDM4EMAPTPOLBSMN1; SMN2 | |
| SCHEMBL30013869 | 0.75 | KDM4E (0.44) | ALDH1A1KDM4EMAPTSMN1; SMN2NPC1 | |
| SCHEMBL405341 | 0.75 | KDM4E (0.44) | ALDH1A1KDM4EMAPTSMN1; SMN2NPC1 | |
| SCHEMBL4650676 | 0.73 | ALDH1A1 (0.48) | ALDH1A1KDM4EMAPTPOLBSMN1; SMN2 | |
| SCHEMBL4752516 | 0.73 | SMN1; SMN2 (0.55) | ALDH1A1KDM4EMAPTPOLBSMN1; SMN2 | |
| SCHEMBL24976102 | 0.72 | LMNA (0.62) | ALDH1A1KDM4EMAPTPOLBSMN1; SMN2 | |
| SCHEMBL30718835 | 0.72 | LMNA (0.62) | ALDH1A1KDM4EMAPTPOLBSMN1; SMN2 | |
| SCHEMBL21877214 | 0.72 | ESR1 (0.50) | ALDH1A1KDM4EMAPTHPGDHTT | |
| SCHEMBL182719 | 0.72 | HTT (0.68) | MAPTMEN1KMT2AHTTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5175261-A | Useful for coloring cellulose materials, animal furs or leather | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-12-29 | — | — | US | disclosed |
| EP-0471454-A1 | Reactive pyridone azo dyestuffs | ZENECA LIMITED (GB) | 1992-02-19 | — | — | EP | disclosed |
| EP-0138303-A1 | Naphthalene sulphonic acids | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1985-04-24 | — | — | EP | disclosed |
| US-4400504-A | DYEING AND PRINTING CELLULOSE AND POLYAMIDE AND-URETHANE FIBERS; TRIAZINE, PYRIDINE AND PYRIMIDINE DYES | BAYER AKTIENGESELLSCHAFT (DE) | 1983-08-23 | — | — | US | disclosed |