SCHEMBL9635994

SCHEMBL9635994

NC(=O)Oc1cc(-c2ccc(N)c(OC(N)=O)c2)ccc1N

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.52
CYP3A4 P08684 4/20 0.52
TDP1 Q9NUW8 4/20 0.52
HSD17B10 Q99714 3/20 0.52
TSHR P16473 3/20 0.52
KMT2A Q03164 5/20 0.47
MEN1 O00255 4/20 0.47
KDM4E B2RXH2 2/20 0.47
MAPK1 P28482 2/20 0.47
POLB P06746 2/20 0.47
MAPT P10636 2/20 0.47
HPGD P15428 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
GFER P55789 1/20 0.45
RXFP1 Q9HBX9 1/20 0.45
IKBKB O14920 1/20 0.43
ALOX15 P16050 1/20 0.41
KIF11 P52732 1/20 0.38
MAP3K11 Q16584 1/20 0.36
CFD P00746 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1954453 0.83 ALDH1A1 (0.52) ALDH1A1CYP3A4TDP1HSD17B10TSHR
SCHEMBL376800 0.83 ALDH1A1 (0.52) ALDH1A1CYP3A4TDP1HSD17B10TSHR
Acetamide SCHEMBL5081796 0.82 ALDH1A1 (0.52) ALDH1A1CYP3A4TDP1HSD17B10TSHR
SCHEMBL8681017 0.82 ALDH1A1 (0.55) ALDH1A1CYP3A4TDP1HSD17B10TSHR
SCHEMBL13735133 0.81 HDAC2 (0.51) HDAC3HDAC1HDAC2
SCHEMBL13735032 0.81 KCNH2 (0.57) HDAC3HDAC1HDAC2
SCHEMBL28471043 0.80 CYP3A4 (0.45) ALDH1A1CYP3A4TDP1HSD17B10TSHR
SCHEMBL27427445 0.80 KEAP1 (0.48) ALDH1A1CYP3A4KMT2AMEN1IKBKB
SCHEMBL9370523 0.79 ALDH1A1 (0.57) ALDH1A1CYP3A4TDP1HSD17B10TSHR
SCHEMBL23568199 0.77 ALDH1A1 (0.46) ALDH1A1CYP3A4TDP1HSD17B10TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0157929-B1 PROCESS FOR PREPARING PRECURSORS OF POLYIMIDES AND POLYISOINDOLO-QUINAZOLINE DIONES SIEMENS AKTIENGESELLSCHAFT (DE) 1988-04-27 EP claimed
EP-0157930-A1 Process for the preparation of polyimide and polyisoindolo-quinazoline dione relief structures SIEMENS AKTIENGESELLSCHAFT (DE) 1985-10-16 EP claimed
EP-0157929-A1 Process for preparing precursors of polyimides and polyisoindolo-quinazoline diones SIEMENS AKTIENGESELLSCHAFT (DE) 1985-10-16 EP claimed
EP-0027506-B1 PRECURSORS OF POLYIMIDES, POLYISOINDOLOQUINAZOLINE DIONES, POLYOXAZINE DIONES AND POLYQUINAZOLINE DIONES, THEIR PREPARATION AND USE SIEMENS AKTIENGESELLSCHAFT (DE) 1983-05-11 EP claimed
EP-0041677-A2 Radiation reactive precursors of highly heat-resistant polymers, and their use SIEMENS AKTIENGESELLSCHAFT (DE) 1981-12-16 EP claimed
EP-0027506-A1 Precursors of polyimides, polyisoindoloquinazoline diones, polyoxazine diones and polyquinazoline diones, their preparation and use SIEMENS AKTIENGESELLSCHAFT (DE) 1981-04-29 EP claimed
EP-0303069-B1 PROCESS FOR THE PREPARATION OF OLIGOMERIC OR POLYMERIC RADIATION-REACTIVE PREADDUCTS FOR SOLVENT-STRUCTURED COATINGS BASF Aktiengesellschaft (DE) 1992-06-24 EP disclosed
EP-0157929-B1 PROCESS FOR PREPARING PRECURSORS OF POLYIMIDES AND POLYISOINDOLO-QUINAZOLINE DIONES SIEMENS AKTIENGESELLSCHAFT (DE) 1988-04-27 EP disclosed
EP-0157930-B1 PROCESS FOR THE PREPARATION OF POLYIMIDE AND POLYISOINDOLO-QUINAZOLINE DIONE RELIEF STRUCTURES SIEMENS AKTIENGESELLSCHAFT (DE) 1988-03-23 EP disclosed
EP-0157930-A1 Process for the preparation of polyimide and polyisoindolo-quinazoline dione relief structures SIEMENS AKTIENGESELLSCHAFT (DE) 1985-10-16 EP disclosed
EP-0157929-A1 Process for preparing precursors of polyimides and polyisoindolo-quinazoline diones SIEMENS AKTIENGESELLSCHAFT (DE) 1985-10-16 EP disclosed
EP-0041678-B1 PROCESS FOR THE PRODUCTION OF HIGHLY HEAT-RESISTANT RELIEF STRUCTURES, AND THEIR USE SIEMENS AKTIENGESELLSCHAFT (DE) 1985-04-10 EP disclosed
EP-0041677-B1 RADIATION REACTIVE PRECURSORS OF HIGHLY HEAT-RESISTANT POLYMERS, AND THEIR USE SIEMENS AKTIENGESELLSCHAFT (DE) 1984-12-27 EP disclosed
EP-0107621-A2 Composition suitable for obtaining positive images, process for obtaining positive images and images obtained using the same CIBA-GEIGY AG (CH) 1984-05-02 EP disclosed
EP-0027506-B1 PRECURSORS OF POLYIMIDES, POLYISOINDOLOQUINAZOLINE DIONES, POLYOXAZINE DIONES AND POLYQUINAZOLINE DIONES, THEIR PREPARATION AND USE SIEMENS AKTIENGESELLSCHAFT (DE) 1983-05-11 EP disclosed
EP-0041677-A2 Radiation reactive precursors of highly heat-resistant polymers, and their use SIEMENS AKTIENGESELLSCHAFT (DE) 1981-12-16 EP disclosed
EP-0041678-A2 Process for the production of highly heat-resistant relief structures, and their use SIEMENS AKTIENGESELLSCHAFT (DE) 1981-12-16 EP disclosed
EP-0027506-A1 Precursors of polyimides, polyisoindoloquinazoline diones, polyoxazine diones and polyquinazoline diones, their preparation and use SIEMENS AKTIENGESELLSCHAFT (DE) 1981-04-29 EP disclosed