Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AMY1A | P0DUB6 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | PDE5A | O76074 | 3/20 | 0.38 |
| ▸ | TEK | Q02763 | 2/20 | 0.38 |
| ▸ | DAO | P14920 | 2/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | PLG | P00747 | 1/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
| ▸ | PLAT | P00750 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.35 |
| ▸ | F7 | P08709 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10847852 | 0.99 | PDE5A (0.39) | AMY1AKDM4ENPSR1PDE5ATEK | |
| SCHEMBL7272073 | 0.87 | KDM4E (0.39) | KDM4ENPSR1PDE5ATEKPDE3B | |
| SCHEMBL7277893 | 0.86 | AMY1A (0.41) | AMY1AKDM4ENPSR1PDE5ATEK | |
| SCHEMBL10738992 | 0.84 | AMY1A (0.41) | AMY1AKDM4ENPSR1PDE5AF2 | |
| SCHEMBL7271721 | 0.84 | PDE5A (0.53) | AMY1AKDM4EPDE5ATEKPDE3B | |
| SCHEMBL7279639 | 0.83 | ALDH1A1 (0.40) | AMY1AKDM4ENPSR1PDE5AF10 | |
| Hydrochloric Acid SCHEMBL7277930 | 0.83 | PDE5A (0.53) | AMY1AKDM4EPDE5ATEKPDE3B | |
| Hydrochloric Acid SCHEMBL9838283 | 0.83 | PDE5A (0.53) | AMY1AKDM4EPDE5ATEKPDE3B | |
| SCHEMBL10987994 | 0.83 | TEK (0.37) | KDM4ENPSR1PDE5ATEKPDE3B | |
| SCHEMBL7281864 | 0.82 | AMY1A (0.57) | AMY1AKDM4ENPSR1PDE5ADAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5104881-A | 2-ARYLIMIDAZOPYRIDINES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-04-14 | — | — | US | disclosed |
| US-4616090-A | 2-arylimidazopyridines intermediates | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1986-10-07 | — | — | US | disclosed |
| EP-0072926-B1 | 2-ARYLIMIDAZOPYRIDINES | MERCK PATENT GmbH (DE) | 1986-09-24 | — | — | EP | disclosed |
| EP-0072926-A1 | 2-Arylimidazopyridines | MERCK PATENT GmbH (DE) | 1983-03-02 | — | — | EP | disclosed |