Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 13/20 | 0.77 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.54 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | DAO | P14920 | 2/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9636066 | 1.00 | APP (0.77) | APPHRH3MAOAMAOBDAO | |
| SCHEMBL8398565 | 0.83 | APP (0.76) | APPHRH3 | |
| SCHEMBL8398561 | 0.83 | APP (0.76) | APPHRH3 | |
| SCHEMBL9637404 | 0.80 | APP (0.70) | APPHRH3ALOX5PTGS1PTGS2 | |
| SCHEMBL9637407 | 0.80 | APP (0.70) | APPHRH3ALOX5PTGS1PTGS2 | |
| SCHEMBL3368559 | 0.78 | APP (0.67) | APPHRH3 | |
| SCHEMBL3370878 | 0.78 | APP (0.67) | APPHRH3 | |
| SCHEMBL9976079 | 0.75 | APP (0.62) | APPHRH3DAOALOX5PTGS1 | |
| SCHEMBL902342 | 0.74 | APP (0.62) | APPHRH3 | |
| SCHEMBL10145183 | 0.71 | APP (0.58) | APPDAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5093505-A | Pyranone and pyran-thione derivatives | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1992-03-03 | — | — | US | disclosed |