Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 9/20 | 0.67 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.54 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3368559 | 0.92 | APP (0.67) | APPHRH3 | |
| SCHEMBL9636066 | 0.78 | APP (0.77) | APPHRH3 | |
| SCHEMBL9636069 | 0.78 | APP (0.77) | APPHRH3 | |
| SCHEMBL8398561 | 0.77 | APP (0.76) | APPHRH3ALDH1A1 | |
| SCHEMBL8398565 | 0.77 | APP (0.76) | APPHRH3ALDH1A1 | |
| SCHEMBL21933269 | 0.77 | CYP19A1 (0.69) | CYP19A1HDAC4HDAC1CYP3A4ATM | |
| SCHEMBL19472000 | 0.76 | CYP19A1 (0.78) | CYP19A1CYP3A4ATMEPHX2HDAC6 | |
| SCHEMBL19500874 | 0.76 | CYP19A1 (0.78) | CYP19A1CYP3A4ATMEPHX2HDAC6 | |
| SCHEMBL9975967 | 0.75 | ALDH1A1 (0.64) | CYP19A1HDAC4HDAC1CYP3A4ATM | |
| SCHEMBL9637407 | 0.74 | APP (0.70) | APPHRH3HSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1515966-B1 | HYDROXY PYRANONE DERIVATIVE AND PREPARATION METHOD THEREOF | AMOREPACIFIC CORP (KR) | 2010-11-03 | — | — | EP | disclosed |
| US-6916844-B2 | Hydroxy pyranone derivative and preparation method thereof | AMOREPACIFIC CORPORATION (KR) | 2005-07-12 | — | — | US | disclosed |
| US-20030236299-A1 | Hydroxy pyranone derivative and preparation method thereof | AMEOREPACIFIC CORPORATION (KR) | 2003-12-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030236299-A1 | Hydroxy pyranone derivative and preparation method thereof | HPD, MMP1, MMP13 | APP 558/4885CYP19A1 194/4885HDAC4 1151/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.