Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.47 |
| ▸ | HMGCR | P04035 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9636049 | 0.90 | SQOR (0.51) | SQORADORA2AADORA1HMGCRKDM4E | |
| SCHEMBL9637289 | 0.85 | SQOR (0.49) | SQORADORA2AADORA1HMGCRKDM4E | |
| SCHEMBL9635988 | 0.84 | SQOR (0.48) | SQORADORA2AADORA1HMGCRKDM4E | |
| SCHEMBL8878013 | 0.82 | SQOR (0.53) | SQORADORA2AADORA1HMGCRKDM4E | |
| SCHEMBL8877064 | 0.80 | SQOR (0.43) | SQORKDM4EALDH1A1LMNAHPGD | |
| SCHEMBL8879993 | 0.79 | HMGCR (0.49) | SQORADORA2AADORA1HMGCRKDM4E | |
| SCHEMBL8877339 | 0.79 | SQOR (0.40) | SQOR | |
| SCHEMBL9636095 | 0.79 | HMGCR (0.41) | SQORHMGCRKDM4EALDH1A1LMNA | |
| SCHEMBL9636004 | 0.77 | KDM4E (0.49) | SQORKDM4EALDH1A1LMNAHPGD | |
| SCHEMBL8953393 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091386-A | Hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-02-25 | — | — | US | disclosed |