Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | NQO2 | P16083 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | MC4R | P32245 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | MC3R | P41968 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 4/20 | 0.36 |
| ▸ | PIM1 | P11309 | 2/20 | 0.35 |
| ▸ | IKBKB | O14920 | 1/20 | 0.35 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.35 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.35 |
| ▸ | NNMT | P40261 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23413382 | 0.88 | LMNA (0.50) | LMNANQO2TSHRADORA3MC4R | |
| SCHEMBL30097519 | 0.88 | LMNA (0.50) | LMNANQO2TSHRADORA3MC4R | |
| SCHEMBL20639210 | 0.84 | LMNA (0.47) | LMNANQO2GRM2IKBKBALDH1A1 | |
| SCHEMBL23413330 | 0.84 | LMNA (0.57) | LMNANQO2SIRT6GRM2PIM1 | |
| SCHEMBL31359268 | 0.84 | LMNA (0.57) | LMNANQO2SIRT6GRM2PIM1 | |
| SCHEMBL22695513 | 0.80 | LMNA (0.42) | LMNANQO2ALDH1A1 | |
| SCHEMBL745813 | 0.79 | TSHR (0.61) | LMNATSHRALOX15HIF1AALDH1A1 | |
| SCHEMBL742374 | 0.79 | TSHR (0.61) | LMNATSHRALOX15HIF1AALDH1A1 | |
| SCHEMBL22540920 | 0.78 | LMNA (0.41) | LMNANQO2GRM2PIM1PIM2 | |
| SCHEMBL17963923 | 0.77 | LMNA (0.54) | LMNANQO2TSHRADORA3MC4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5094759-A | Method of water treatment using 2,6-substituted aminopyridines and polymer derived therefrom | THE UNIVERSITY OF SOUTHERN MISSISSIPPI (US) | 1992-03-10 | — | — | US | disclosed |
| US-5026802-A | Polymers derived from 2,6-substituted-4-amino-pyridines | THE UNIVERSITY OF SOUTHERN MISSISSIPPI (US) | 1991-06-25 | — | — | US | disclosed |
| US-4940796-A | 2,6-substituted-4-aminopyridines and their corresponding intermediates | THE UNIVERSITY OF SOUTHERN MISSISSIPPI (US) | 1990-07-10 | — | — | US | disclosed |