SCHEMBL742374

SCHEMBL742374

Nc1cc(C(=O)O)nc(C(=O)O)c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.61
ALOX15 P16050 3/20 0.61
HIF1A Q16665 2/20 0.61
KDM4E B2RXH2 7/20 0.50
TDP1 Q9NUW8 5/20 0.50
ACMSD Q8TDX5 1/20 0.50
MEN1 O00255 4/20 0.41
KMT2A Q03164 4/20 0.41
ALDH1A1 P00352 4/20 0.41
LMNA P02545 2/20 0.41
DDO Q99489 1/20 0.41
IGFBP3 P17936 1/20 0.41
GPR35 Q9HC97 1/20 0.38
MCL1 Q07820 2/20 0.37
MAPT P10636 4/20 0.37
THRB P10828 2/20 0.37
RECQL P46063 2/20 0.37
CYP3A4 P08684 2/20 0.37
KDM5A P29375 2/20 0.37
KDM3A Q9Y4C1 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL745813 1.00 TSHR (0.61) TSHRALOX15HIF1AKDM4ETDP1
SCHEMBL29254156 0.97 TSHR (0.58) TSHRALOX15HIF1AKDM4ETDP1
SCHEMBL30938840 0.97 TSHR (0.58) TSHRALOX15HIF1AKDM4ETDP1
SCHEMBL23832824 0.84 ALOX15 (0.45) TSHRALOX15HIF1AKDM4ETDP1
SCHEMBL16030719 0.84 HIF1A (0.45) TSHRALOX15HIF1AKDM4ETDP1
SCHEMBL6391471 0.84 NQO2 (0.50) TSHRALOX15HIF1AKDM4ETDP1
SCHEMBL27077029 0.80 ALOX15 (0.41) TSHRALOX15HIF1AKDM4EALDH1A1
SCHEMBL23718185 0.80 TDP1 (0.42) TSHRALOX15HIF1AKDM4ETDP1
SCHEMBL30697188 0.80 ALOX15 (0.41) TSHRALOX15HIF1AKDM4EALDH1A1
SCHEMBL9636253 0.79 LMNA (0.56) TSHRALOX15HIF1AALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118082338-B Medical multi-layer wristband and preparation method thereof 广州爱德医疗科技有限公司 2025-05-02 CN claimed
CN-116240548-B Etching solution for selectively etching AlCu layer relative to laminated metal and preparation method thereof 湖北兴福电子材料股份有限公司 2025-01-14 CN claimed
CN-118892723-A Desulfurization method by using circulating hydrogen desulfurization tower 宁波博盈新材料有限公司 2024-11-05 CN claimed
CN-118724643-A Preparation method of water-retaining litchi flower-promoting foliar fertilizer 华南农业大学 2024-10-01 CN claimed
CN-118546493-A Preparation method of novel low-resin-base brake pad 浙江万赛汽车零部件股份有限公司 2024-08-27 CN claimed
CN-118126556-A Preparation method of intrinsic antibacterial material 浙江世瑞骐碳科技有限公司 2024-06-04 CN claimed
CN-118082338-A Medical multi-layer wristband and preparation method thereof 广州爱德医疗科技有限公司 2024-05-28 CN claimed
CN-118006059-A Oxidation-resistant seven-hole plum blossom honeycomb tube and preparation method thereof 安庆市悦发管业有限公司 2024-05-10 CN claimed
CN-117417228-A Method for one-step separation and purification of ethylene based on stable metal-organic framework material rich in Lewis alkaline sites 浙江大学 2024-01-19 CN claimed
CN-114892406-A Preparation method of high-fluffiness hydrophobic down feather fibers 安徽古麒绒材股份有限公司 2022-08-12 CN claimed
US-10590343-B2 Corrosion inhibitor composition for magnesium or magnesium alloys Helmholtz-Zentrum Geesthacht Zentrum für Material-und Küstenforschung GmbH (DE) 2020-03-17 US claimed
EP-3284847-B1 CORROSION INHIBITOR COMPOSITION FOR MAGNESIUM OR MAGNESIUM ALLOYS HELMHOLTZ ZENTRUM GEESTHACHT (DE) 2019-01-02 EP claimed
EP-3284847-A1 CORROSION INHIBITOR COMPOSITION FOR MAGNESIUM OR MAGNESIUM ALLOYS Helmholtz-Zentrum Geesthacht Zentrum für Material- und Küstenforschung GmbH (DE) 2018-02-21 EP claimed
US-20180044590-A1 Corrosion Inhibitor Composition for Magnesium or Magnesium Alloys Helmholtz-Zentrum Geesthacht Zentrum für Material-und Küstenforschung GmbH (DE) 2018-02-15 US claimed
US-5821074-A ANALYZING FOR LEAD ABBOTT LABORATORIES (US) 1998-10-13 US claimed
CN-118082338-B Medical multi-layer wristband and preparation method thereof 广州爱德医疗科技有限公司 2025-05-02 CN disclosed
CN-118892723-A Desulfurization method by using circulating hydrogen desulfurization tower 宁波博盈新材料有限公司 2024-11-05 CN disclosed
US-20070100024-A1 Modified colorants and inkjet ink compositions comprising modified colorants CABOT CORPORATION 2007-05-03 US disclosed
US-5821074-A ANALYZING FOR LEAD ABBOTT LABORATORIES (US) 1998-10-13 US disclosed
US-5597702-A ENZYME INHIBITOR ABBOTT LABORATORIES (US) 1997-01-28 US disclosed