Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 1/20 | 0.63 |
| ▸ | GPR4 | P46093 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TACR2 | P21452 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL9636289 | 1.00 | SLC6A9 (0.63) | SLC6A9GPR4MEN1KMT2ACHRM5 | |
| Oxalic Acid SCHEMBL9634587 | 0.89 | SLC6A9 (0.65) | SLC6A9MEN1KMT2ACHRM5CHRM1 | |
| Oxalic Acid SCHEMBL9870147 | 0.87 | SLC6A9 (0.66) | SLC6A9MEN1KMT2ACHRM5CHRM1 | |
| Oxalic Acid SCHEMBL9870156 | 0.87 | SLC6A9 (0.66) | SLC6A9MEN1KMT2ACHRM5CHRM1 | |
| Oxalic Acid SCHEMBL9636284 | 0.87 | SLC6A9 (0.61) | SLC6A9MEN1KMT2ACHRM5CHRM1 | |
| Oxalic Acid SCHEMBL9636291 | 0.86 | SLC6A9 (0.60) | SLC6A9MEN1KMT2ACHRM5CHRM1 | |
| Oxalic Acid SCHEMBL9636288 | 0.86 | SLC6A9 (0.60) | SLC6A9MEN1KMT2ACHRM5CHRM1 | |
| Oxalic Acid SCHEMBL9634632 | 0.86 | SLC6A9 (0.60) | SLC6A9MEN1KMT2ACHRM5CHRM1 | |
| Oxalic Acid SCHEMBL9634639 | 0.86 | SLC6A9 (0.60) | SLC6A9MEN1KMT2ACHRM5CHRM1 | |
| Hydrochloric Acid SCHEMBL9636312 | 0.86 | SLC6A9 (0.64) | SLC6A9MEN1KMT2ACHRM5CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0307014-B1 | ANTI-ALLERGIC 2-(HETEROCYCLYL ALKYL) IMIDAZO PYRIDINES AND 2-(HETEROCYCLYL ALKYL) PURINES | JANSSEN PHARMACEUTICA N.V. (BE) | 1992-12-09 | — | — | EP | disclosed |
| US-5086056-A | Treating allergic diseases | JANSSEN PHARMACEUTICA N.V. (BE) | 1992-02-04 | — | — | US | disclosed |
| US-5011842-A | Antihistamines | JANSSEN PHARMACEUTICA N.V. (BE) | 1991-04-30 | — | — | US | disclosed |
| US-4946843-A | ANTIALLERGENS | JANSSEN PHARMACEUTICA N.V. (BE) | 1990-08-07 | — | — | US | disclosed |