Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 1/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | HRH1 | P35367 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL9634587 | 0.95 | SLC6A9 (0.65) | SLC6A9KDM4ETSHRPOLBHRH1 | |
| SCHEMBL9685926 | 0.90 | SLC6A9 (0.68) | SLC6A9KDM4ETSHRALDH1A1CHRM5 | |
| SCHEMBL9686512 | 0.90 | SLC6A9 (0.68) | SLC6A9TSHRALDH1A1CHRM5CHRM1 | |
| SCHEMBL9635911 | 0.89 | SLC6A9 (0.68) | SLC6A9KDM4ETSHRHRH1ALDH1A1 | |
| SCHEMBL10444904 | 0.89 | SLC6A9 (0.67) | SLC6A9TSHRALDH1A1CHRM5CHRM1 | |
| SCHEMBL9634560 | 0.88 | SLC6A9 (0.67) | SLC6A9KDM4ETSHRHRH1ALDH1A1 | |
| SCHEMBL9685783 | 0.86 | SLC6A9 (0.64) | SLC6A9KDM4EALDH1A1CHRM5CHRM1 | |
| SCHEMBL9635855 | 0.86 | SLC6A9 (0.64) | SLC6A9KDM4ETSHRALDH1A1CHRM5 | |
| Hydrochloric Acid SCHEMBL9636312 | 0.86 | SLC6A9 (0.64) | SLC6A9KDM4ETSHRALDH1A1CHRM5 | |
| SCHEMBL9684843 | 0.86 | SLC6A9 (0.64) | SLC6A9KDM4ETSHRHRH1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0307014-B1 | ANTI-ALLERGIC 2-(HETEROCYCLYL ALKYL) IMIDAZO PYRIDINES AND 2-(HETEROCYCLYL ALKYL) PURINES | JANSSEN PHARMACEUTICA N.V. (BE) | 1992-12-09 | — | — | EP | disclosed |
| US-5086056-A | Treating allergic diseases | JANSSEN PHARMACEUTICA N.V. (BE) | 1992-02-04 | — | — | US | disclosed |
| US-5011842-A | Antihistamines | JANSSEN PHARMACEUTICA N.V. (BE) | 1991-04-30 | — | — | US | disclosed |
| US-4946843-A | ANTIALLERGENS | JANSSEN PHARMACEUTICA N.V. (BE) | 1990-08-07 | — | — | US | disclosed |