Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9536111 | 0.90 | SLC6A9 (0.44) | SLC6A9TSHRBACE1MEN1KMT2A | |
| Fumaric Acid SCHEMBL10383229 | 0.84 | SLC6A9 (0.41) | SLC6A9TSHRMEN1KMT2AMAPT | |
| Fumaric Acid SCHEMBL10382851 | 0.80 | SLC6A9 (0.37) | SLC6A9TSHRMEN1KMT2AMAPT | |
| Oxalic Acid SCHEMBL9636339 | 0.80 | SLC6A9 (0.56) | SLC6A9MEN1KMT2AALDH1A1PKM | |
| SCHEMBL10444904 | 0.79 | SLC6A9 (0.67) | SLC6A9TSHRMEN1KMT2AALDH1A1 | |
| Oxalic Acid SCHEMBL9634855 | 0.79 | SLC6A9 (0.61) | SLC6A9MEN1KMT2AALDH1A1CHRM5 | |
| Oxalic Acid SCHEMBL9634849 | 0.79 | SLC6A9 (0.61) | SLC6A9MEN1KMT2AALDH1A1CHRM5 | |
| SCHEMBL9685926 | 0.79 | SLC6A9 (0.68) | SLC6A9TSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL9686512 | 0.79 | SLC6A9 (0.68) | SLC6A9TSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL9687136 | 0.78 | SLC6A9 (0.55) | SLC6A9MEN1KMT2AALDH1A1CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0307014-B1 | ANTI-ALLERGIC 2-(HETEROCYCLYL ALKYL) IMIDAZO PYRIDINES AND 2-(HETEROCYCLYL ALKYL) PURINES | JANSSEN PHARMACEUTICA N.V. (BE) | 1992-12-09 | — | — | EP | disclosed |
| US-5086056-A | Treating allergic diseases | JANSSEN PHARMACEUTICA N.V. (BE) | 1992-02-04 | — | — | US | disclosed |
| US-5011842-A | Antihistamines | JANSSEN PHARMACEUTICA N.V. (BE) | 1991-04-30 | — | — | US | disclosed |
| US-4946843-A | ANTIALLERGENS | JANSSEN PHARMACEUTICA N.V. (BE) | 1990-08-07 | — | — | US | disclosed |
| EP-0307014-A1 | Anti-allergic 2-(heterocyclyl alkyl) imidazo pyridines and 2-(heterocyclyl alkyl) purines | JANSSEN PHARMACEUTICA N.V. (BE) | 1989-03-15 | — | — | EP | disclosed |