Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.36 |
| ▸ | HRH1 | P35367 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | HTR1D | P28221 | 1/20 | 0.33 |
| ▸ | HTR1B | P28222 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fumaric Acid SCHEMBL10383229 | 0.94 | SLC6A9 (0.41) | SLC6A9TSHRKDM4ELMNASMN1; SMN2 | |
| SCHEMBL9636352 | 0.90 | SLC6A9 (0.55) | SLC6A9TSHRSMN1; SMN2MEN1KMT2A | |
| SCHEMBL9535432 | 0.85 | TP53 (0.40) | SLC6A9TSHRLMNA | |
| SCHEMBL9537795 | 0.85 | TSHR (0.41) | SLC6A9TSHRKDM4ESMN1; SMN2HRH1 | |
| SCHEMBL9537396 | 0.84 | SLC6A9 (0.48) | SLC6A9TSHRLMNA | |
| SCHEMBL9536208 | 0.83 | SLC6A9 (0.41) | SLC6A9TSHRKDM4ELMNAMEN1 | |
| SCHEMBL9536927 | 0.83 | SLC6A9 (0.56) | SLC6A9TSHR | |
| SCHEMBL10803216 | 0.82 | SLC6A9 (0.40) | SLC6A9TSHRHTR1AHTR1DHTR1B | |
| Fumaric Acid SCHEMBL10382851 | 0.81 | SLC6A9 (0.37) | SLC6A9TSHRHRH1MEN1KMT2A | |
| Oxalic Acid SCHEMBL9535391 | 0.80 | SLC6A9 (0.47) | SLC6A9KDM4ELMNASMN1; SMN2HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0282133-B1 | 1-ALKYL SUBSTITUTED BENZIMIDAZOLE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1993-07-28 | — | — | EP | disclosed |