Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.35 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5941284 | 0.73 | SMN1; SMN2 (0.39) | ACECYP1A2CYP2D6GRM2GRM3 | |
| SCHEMBL21473271 | 0.69 | ACE (0.45) | ACECYP2D6AOC3LMNAALDH1A1 | |
| SCHEMBL11389638 | 0.69 | ACE (0.44) | ACEAOC3LMNAALDH1A1HIF1A | |
| SCHEMBL21632771 | 0.66 | CYP1A2 (0.44) | CYP1A2CYP2D6GRM2GRM3LMNA | |
| SCHEMBL11182324 | 0.66 | ACE (0.49) | ACECYP1A2CYP2D6GRM2GRM3 | |
| SCHEMBL5328203 | 0.65 | TAAR1 (0.46) | CYP1A2CYP2D6GRM2GRM3AOC3 | |
| SCHEMBL8198281 | 0.65 | SMN1; SMN2 (0.42) | CYP1A2CYP2D6GRM2GRM3AOC3 | |
| SCHEMBL10700271 | 0.65 | HTR2A (0.43) | ACELMNA | |
| SCHEMBL20241828 | 0.64 | CYP1A2 (0.55) | CYP1A2CYP2D6GRM2GRM3GAA | |
| SCHEMBL21528472 | 0.64 | CYP1A2 (0.55) | CYP1A2CYP2D6GRM2GRM3GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5084007-A | Method for chemical promotion of the effects of low current transcranial electrostimulation | MALIN DAVID H (US) | 1992-01-28 | — | — | US | disclosed |
| WO-1991001756-A1 | METHOD FOR CHEMICAL PROMOTION OF THE EFFECTS OF LOW CURRENT TRANSCRANIAL ELECTROSTIMULATION | SKOLNICK MALCOLM H (US) | 1991-02-21 | — | — | WO | disclosed |