Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 12/20 | 0.72 |
| ▸ | ABCC4 | O15439 | 5/20 | 0.72 |
| ▸ | VDR | P11473 | 2/20 | 0.72 |
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.62 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.61 |
| ▸ | SLC10A2 | Q12908 | 3/20 | 0.59 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.59 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.59 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.59 |
| ▸ | SLC10A1 | Q14973 | 3/20 | 0.54 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8769124 | 0.92 | GPBAR1 (0.61) | GPBAR1ABCC4VDRNR1H4EPHA2 | |
| SCHEMBL5667769 | 0.88 | GPBAR1 (0.74) | GPBAR1ABCC4VDRNR1H4EPHA2 | |
| SCHEMBL6698178 | 0.88 | GPBAR1 (0.74) | GPBAR1ABCC4VDRNR1H4EPHA2 | |
| SCHEMBL19360934 | 0.88 | GPBAR1 (0.79) | GPBAR1ABCC4VDRNR1H4EPHA2 | |
| SCHEMBL22727926 | 0.88 | GPBAR1 (0.79) | GPBAR1ABCC4VDRNR1H4EPHA2 | |
| SCHEMBL25170335 | 0.88 | GPBAR1 (0.79) | GPBAR1ABCC4VDRNR1H4EPHA2 | |
| SCHEMBL6369959 | 0.88 | GPBAR1 (0.79) | GPBAR1ABCC4VDRNR1H4EPHA2 | |
| SCHEMBL17641180 | 0.88 | GPBAR1 (0.79) | GPBAR1ABCC4VDRNR1H4EPHA2 | |
| SCHEMBL7146262 | 0.86 | GPBAR1 (0.70) | GPBAR1ABCC4VDRNR1H4EPHA2 | |
| Taurolithocholic Acid SCHEMBL22727921 | 0.83 | GPBAR1 (1.00) | GPBAR1ABCC4VDRNR1H4EPHA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0286367-B1 | STABILIZATION OF BETA-GALACTOSIDASE PEPTIDE FRAGMENTS | MICROGENICS CORPORATION (a Delaware corporation) (US) | 1992-07-08 | — | — | EP | disclosed |
| EP-0286367-A2 | Stabilization of beta-galactosidase peptide fragments | MICROGENICS CORPORATION (a Delaware corporation) (US) | 1988-10-12 | — | — | EP | disclosed |