Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 12/20 | 0.74 |
| ▸ | ABCC4 | O15439 | 4/20 | 0.74 |
| ▸ | VDR | P11473 | 2/20 | 0.74 |
| ▸ | SLC10A2 | Q12908 | 3/20 | 0.63 |
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.61 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.61 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.61 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.61 |
| ▸ | SLC10A1 | Q14973 | 3/20 | 0.58 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.56 |
| ▸ | ST6GAL1 | P15907 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5667769 | 1.00 | GPBAR1 (0.74) | GPBAR1ABCC4VDRSLC10A2NR1H4 | |
| SCHEMBL9636455 | 0.88 | GPBAR1 (0.72) | GPBAR1ABCC4VDRSLC10A2NR1H4 | |
| SCHEMBL5667778 | 0.86 | GPBAR1 (0.74) | GPBAR1ABCC4VDRSLC10A2NR1H4 | |
| SCHEMBL4331335 | 0.86 | GPBAR1 (0.73) | GPBAR1ABCC4VDRSLC10A2NR1H4 | |
| Taurolithocholic Acid SCHEMBL24001385 | 0.85 | GPBAR1 (1.00) | GPBAR1ABCC4VDRSLC10A2NR1H4 | |
| Taurolithocholic Acid SCHEMBL20065899 | 0.85 | GPBAR1 (1.00) | GPBAR1ABCC4VDRSLC10A2NR1H4 | |
| Taurolithocholic Acid SCHEMBL18762171 | 0.85 | GPBAR1 (1.00) | GPBAR1ABCC4VDRSLC10A2NR1H4 | |
| Taurolithocholic Acid SCHEMBL22727921 | 0.85 | GPBAR1 (1.00) | GPBAR1ABCC4VDRSLC10A2NR1H4 | |
| Taurolithocholic Acid SCHEMBL17309133 | 0.85 | GPBAR1 (1.00) | GPBAR1ABCC4VDRSLC10A2NR1H4 | |
| Taurolithocholic Acid SCHEMBL364160 | 0.85 | GPBAR1 (1.00) | GPBAR1ABCC4VDRSLC10A2NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040229831-A1 | Compositions and methods for non-parenteral delivery of oligonucleotides | ISIS PHARMACEUTICALS, INC. | 2004-11-18 | — | — | US | disclosed |