Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 11/20 | 0.61 |
| ▸ | ABCC4 | O15439 | 5/20 | 0.61 |
| ▸ | VDR | P11473 | 2/20 | 0.61 |
| ▸ | EPHA2 | P29317 | 3/20 | 0.60 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.53 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.51 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.51 |
| ▸ | EFNA1 | P20827 | 1/20 | 0.51 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.51 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.51 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.51 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.51 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.51 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9636455 | 0.92 | GPBAR1 (0.72) | GPBAR1ABCC4VDREPHA2NR1H4 | |
| SCHEMBL7146262 | 0.85 | GPBAR1 (0.70) | GPBAR1ABCC4VDREPHA2NR1H4 | |
| SCHEMBL4751618 | 0.82 | GPBAR1 (0.74) | GPBAR1ABCC4VDREPHA2NR1H4 | |
| SCHEMBL10906860 | 0.82 | GPBAR1 (0.74) | GPBAR1ABCC4VDREPHA2NR1H4 | |
| SCHEMBL381612 | 0.82 | GPBAR1 (0.74) | GPBAR1ABCC4VDREPHA2NR1H4 | |
| SCHEMBL11573739 | 0.81 | GPBAR1 (0.60) | GPBAR1VDREPHA2NR1H4AKR1B10 | |
| SCHEMBL6698178 | 0.81 | GPBAR1 (0.74) | GPBAR1ABCC4VDREPHA2NR1H4 | |
| SCHEMBL5667769 | 0.81 | GPBAR1 (0.74) | GPBAR1ABCC4VDREPHA2NR1H4 | |
| SCHEMBL25170335 | 0.80 | GPBAR1 (0.79) | GPBAR1ABCC4VDREPHA2NR1H4 | |
| SCHEMBL19360934 | 0.80 | GPBAR1 (0.79) | GPBAR1ABCC4VDREPHA2NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0793967-A2 | Conjugated compounds of bile acids with thiotaurine and its N-alkyl derivatives | PRODOTTI CHIMICI E ALIMENTARI SPA (IT) | 1997-09-10 | — | — | EP | disclosed |