Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | TLR4 | O00206 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | NPEPPS | P55786 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8836678 | 0.81 | ALDH1A1 (0.36) | ALDH1A1ALOX12TLR4L3MBTL1HTT | |
| SCHEMBL10557795 | 0.81 | ALDH1A1 (0.36) | ALDH1A1ALOX12TLR4L3MBTL1HTT | |
| SCHEMBL9331617 | 0.81 | ALDH1A1 (0.36) | ALDH1A1ALOX12TLR4L3MBTL1HTT | |
| SCHEMBL9636502 | 0.80 | ALDH1A1 (0.41) | ALDH1A1ALOX12TLR4L3MBTL1HTT | |
| SCHEMBL9729328 | 0.78 | ALDH1A1 (0.45) | ALDH1A1ALOX12L3MBTL1HTTKDM4E | |
| SCHEMBL9729321 | 0.78 | ALDH1A1 (0.45) | ALDH1A1ALOX12L3MBTL1HTTKDM4E | |
| SCHEMBL9680763 | 0.78 | ALDH1A1 (0.34) | ALDH1A1ALOX12L3MBTL1HTTKDM4E | |
| SCHEMBL9637776 | 0.77 | ALDH1A1 (0.43) | ALDH1A1ALOX12L3MBTL1HTTKDM4E | |
| SCHEMBL1869315 | 0.75 | ALDH1A1 (0.41) | ALDH1A1ALOX12TLR4L3MBTL1HTT | |
| SCHEMBL11258088 | 0.74 | ALDH1A1 (0.40) | ALDH1A1ALOX12L3MBTL1HTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0272202-B1 | Process for the preparation of optically active bicyclo[3.3.0]octanedione-carboxylic-acid esters | SCHERING AKTIENGESELLSCHAFT (DE) | 1992-07-01 | — | — | EP | disclosed |
| US-5093250-A | Process for producing optically active bicyclo[3.3.0]octanedione carboxylic acid esters | SCHERING AKTIENGESELLSCHAFT (DE) | 1992-03-03 | — | — | US | disclosed |
| EP-0272202-A1 | Process for the preparation of optically active bicyclo[3.3.0]octanedione-carboxylic-acid esters | SCHERING AKTIENGESELLSCHAFT (DE) | 1988-06-22 | — | — | EP | disclosed |
| WO-1988003569-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE BICYCLO[3.3.0]OCTANDIONE CARBOXYLIC ACID ESTERS | SCHERING AKTIENGESELLSCHAFT (DE) | 1988-05-19 | — | — | WO | disclosed |