Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | NPEPPS | P55786 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9729321 | 0.84 | ALDH1A1 (0.45) | ALDH1A1ALOX12MEN1KMT2AKDM4E | |
| SCHEMBL9729328 | 0.84 | ALDH1A1 (0.45) | ALDH1A1ALOX12MEN1KMT2AKDM4E | |
| SCHEMBL9636452 | 0.81 | ALDH1A1 (0.40) | ALDH1A1KMT2AKDM4EHTTTSHR | |
| SCHEMBL9729462 | 0.81 | ALDH1A1 (0.40) | ALDH1A1KMT2AKDM4EHTTTSHR | |
| SCHEMBL1869315 | 0.81 | ALDH1A1 (0.41) | ALDH1A1ALOX12MEN1KMT2AKDM4E | |
| SCHEMBL11258088 | 0.80 | ALDH1A1 (0.40) | ALDH1A1ALOX12MEN1KMT2AKDM4E | |
| SCHEMBL9636564 | 0.79 | ALDH1A1 (0.44) | ALDH1A1ALOX12MEN1KMT2AKDM4E | |
| SCHEMBL9636595 | 0.77 | ALDH1A1 (0.36) | ALDH1A1ALOX12MEN1KMT2AKDM4E | |
| SCHEMBL9331617 | 0.75 | ALDH1A1 (0.36) | ALDH1A1ALOX12MEN1KMT2AKDM4E | |
| SCHEMBL10557795 | 0.75 | ALDH1A1 (0.36) | ALDH1A1ALOX12MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0272202-B1 | Process for the preparation of optically active bicyclo[3.3.0]octanedione-carboxylic-acid esters | SCHERING AKTIENGESELLSCHAFT (DE) | 1992-07-01 | — | — | EP | disclosed |
| US-5093250-A | Process for producing optically active bicyclo[3.3.0]octanedione carboxylic acid esters | SCHERING AKTIENGESELLSCHAFT (DE) | 1992-03-03 | — | — | US | disclosed |