Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.46 |
| ▸ | TYR | P14679 | 3/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4659133 | 0.85 | NPC1 (0.48) | GABRA1GABRB2TYRHTTNPC1 | |
| SCHEMBL28636752 | 0.84 | TYR (0.39) | TYRALOX5HTTNPC1HPGD | |
| SCHEMBL8370068 | 0.84 | EGFR (0.41) | TYRALOX5HTTNPC1HPGD | |
| SCHEMBL201692 | 0.82 | NPC1 (0.57) | TYRALOX5HTTNPC1HPGD | |
| SCHEMBL4798703 | 0.81 | GABRA1 (0.69) | GABRA1GABRB2TYRALOX5HTT | |
| SCHEMBL8517221 | 0.81 | EGFR (0.43) | GABRA1GABRB2TYRALOX5HTT | |
| SCHEMBL11796160 | 0.81 | TYR (0.39) | TYRALOX5HTTNPC1HPGD | |
| SCHEMBL11795637 | 0.80 | GABRA1 (0.39) | GABRA1GABRB2ALOX5NPSR1PTGS2 | |
| SCHEMBL6314093 | 0.80 | HTT (0.50) | TYRALOX5HTTNPC1HPGD | |
| SCHEMBL27977349 | 0.80 | NPC1 (0.55) | TYRALOX5HTTNPC1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0489050-A1 | ARYL ESTER AMIDE HALIDES OF PHOSPHONOUS ACID, ARYL ESTER AMIDES OF PHOSPHONOUS ACID, PROCESS FOR PREPARING THEM AND THEIR USE TO STABILIZE PLASTICS | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-06-10 | — | — | EP | disclosed |
| WO-1991002738-A1 | ARYL ESTER AMIDE HALIDES OF PHOSPHONOUS ACID, ARYL ESTER AMIDES OF PHOSPHONOUS ACID, PROCESS FOR PREPARING THEM AND THEIR USE TO STABILIZE PLASTICS | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-03-07 | — | — | WO | disclosed |