SCHEMBL4659133

SCHEMBL4659133

CCCCc1cc(CC(C)C)c(O)c(CC(C)C)c1

nearest known ligand 0.48

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.48
RAB9A P51151 2/20 0.48
HPGD P15428 1/20 0.48
MAPK1 P28482 1/20 0.48
HTT P42858 1/20 0.48
NPSR1 Q6W5P4 1/20 0.48
GABRA1 P14867 2/20 0.47
GABRB2 P47870 2/20 0.47
PTGS2 P35354 4/20 0.46
CYP3A4 P08684 1/20 0.46
TYR P14679 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.37
GPR84 Q9NQS5 1/20 0.37
SKP2 Q13309 1/20 0.37
FFAR1 O14842 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28720288 0.95 PTGS2 (0.53) NPC1RAB9AHPGDMAPK1HTT
SCHEMBL18554681 0.93 PTGS2 (0.55) NPC1RAB9AHPGDMAPK1HTT
SCHEMBL16182674 0.89 GABRA1 (0.50) NPC1RAB9AHPGDMAPK1HTT
SCHEMBL9636655 0.85 GABRA1 (0.46) NPC1RAB9AHPGDMAPK1HTT
SCHEMBL9194816 0.84 GABRA1 (0.40) NPC1RAB9AHPGDMAPK1HTT
SCHEMBL11795983 0.82 NPC1 (0.37) NPC1RAB9AHPGDMAPK1HTT
SCHEMBL201692 0.82 NPC1 (0.57) NPC1RAB9AHPGDMAPK1HTT
SCHEMBL5164394 0.81 GABRA1 (0.69) NPC1RAB9AHPGDMAPK1HTT
SCHEMBL8342795 0.80 GABRA1 (0.54) RAB9AHPGDMAPK1GABRA1GABRB2
SCHEMBL1023228 0.80 NPC1 (0.55) NPC1RAB9AHPGDMAPK1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1646686-B1 POLYMER COMPOSITION, PROCESS FOR PRODUCING THE POLYMER COMPOSITION, AND MOLDED ARTICLES FOR AUTOMOBILE EXTERIOR TRIM MITSUI DU PONT POLYCHEMICAL (JP) 2008-12-10 EP disclosed
EP-1892263-A2 Polymer composition, process for producing the polymer composition, and molded articles for automobile exterior trim. Du Pont-Mitsui Polychemicals Co., Ltd. (JP) 2008-02-27 EP disclosed
US-20070299181-A1 Polymer composition, process for producing the polymer composition, and molded articles for automobile exterior trim DU PONT-MITSUI POLYCHEMICALS CO., LTD. (JP) 2007-12-27 US disclosed
US-20070149707-A1 Polymer composition, process for producing the polymer composition, and molded articles for automobile exterior trim DU PONT-MITSUI POLYCHEMICALS CO., LTD. (JP) 2007-06-28 US disclosed
CN-1852944-A Polymer composition, process for producing the same, and molded article for automobile exterior trim MITSUI DU PONT POLYCHEMICAL (JP) 2006-10-25 CN disclosed
EP-1646686-A2 POLYMER COMPOSITION, PROCESS FOR PRODUCING THE POLYMER COMPOSITION, AND MOLDED ARTICLES FOR AUTOMOBILE EXTERIOR TRIM Du Pont-Mitsui Polychemicals Co., Ltd. (JP) 2006-04-19 EP disclosed
EP-1273596-B1 FLEXIBLE POLYPROPYLENE RESIN IDEMITSU KOSAN CO (JP) 2005-03-30 EP disclosed
US-6855756-B2 Soft polypropylene resin having a melt index falling in a specific range, prepared by melting and kneading a propylene homo or copolymer each having specific properties in presence of a radical generating agent IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2005-02-15 US disclosed
WO-2004104087-A2 POLYMER COMPOSITION, PROCESS FOR PRODUCING THE POLYMER COMPOSITION, AND MOLDED ARTICLES FOR AUTOMOBILE EXTERIOR TRIM DU PONT-MITSUI POLYCHEMICALS CO., LTD. (JP) 2004-12-02 WO disclosed
US-20030055137-A1 Soft polypropylene resin having a melt index falling in a specific range, prepared by melting and kneading a propylene homo or copolymer each having specific properties in presence of a radical generating agent PRIME POLYMER CO., LTD. (JP) 2003-03-20 US disclosed
EP-1273596-A1 FLEXIBLE POLYPROPYLENE RESIN IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2003-01-08 EP disclosed
EP-0416321-B1 Crystalline polyolefin composition CHISSO CORP (JP) 1994-11-09 EP disclosed
US-5141995-A Melting, kneading and Blending with polyol fatty acid, phenolic antioxidant, radical generating agent CHISSO CORPORATION (JP) 1992-08-25 US disclosed
EP-0242785-B1 PROCESS FOR PRODUCING A MODIFIED PROPYLENE POLYMER Chisso Corporation (JP) 1992-02-19 EP disclosed
US-5063264-A Molding materials CHISSO CORPORATION (JP) 1991-11-05 US disclosed
EP-0416321-A1 Crystalline polyolefin composition Chisso Corporation (JP) 1991-03-13 EP disclosed
US-4923918-A MELT KNEADING WITH RADICAL GENERATOR, PHENOLIC ANTIOXIDANT, VANADIUM OR TITANIUM CATALYST RESIDUE AND ZINC CARBOXYLATE; COLORLESS, MOLDABILITY CHISSO CORPORATION (JP) 1990-05-08 US disclosed
EP-0242785-A2 Process for producing a modified propylene polymer Chisso Corporation (JP) 1987-10-28 EP disclosed