Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.45 |
| ▸ | HTR3B | O95264 | 2/20 | 0.45 |
| ▸ | HTR3A | P46098 | 2/20 | 0.45 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.45 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | GSK3B | P49841 | 3/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | NOS3 | P29474 | 2/20 | 0.39 |
| ▸ | NOS1 | P29475 | 2/20 | 0.39 |
| ▸ | NOS2 | P35228 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30511829 | 0.72 | — | — | |
| SCHEMBL629482 | 0.72 | — | — | |
| SCHEMBL17372822 | 0.71 | MEN1 (0.40) | NPC1NOS3NOS1NOS2ALDH1A1 | |
| SCHEMBL11559449 | 0.71 | GAA (0.54) | TSHRNPC1MAPTALDH1A1RAB9A | |
| SCHEMBL28913620 | 0.71 | SMN1; SMN2 (0.54) | LMNATSHRNPC1MAPTALDH1A1 | |
| SCHEMBL7294187 | 0.71 | TSHR (0.41) | LMNATSHRNPC1ESR1ESR2 | |
| SCHEMBL3194959 | 0.71 | HTR3E (0.54) | LMNATSHRHTR3EHTR3BHTR3A | |
| SCHEMBL8964884 | 0.71 | MAPT (0.57) | LMNATSHRHTR3EHTR3BHTR3A | |
| SCHEMBL861925 | 0.71 | MAPT (0.57) | LMNATSHRHTR3EHTR3BHTR3A | |
| SCHEMBL11568361 | 0.70 | MPI (0.45) | LMNANPC1MAPTALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5080764-A | NOVEL POLYMERIC NONLINEAR OPTICAL MATERIALS FROM ANISOTROPIC DIPOLAR MONOMERS | THE DOW CHEMICAL COMPANY (US) | 1992-01-14 | — | — | US | disclosed |
| EP-0430139-A2 | Polymeric nonlinear optical materials from anisotropic dipolar monomers | THE DOW CHEMICAL COMPANY (US) | 1991-06-05 | — | — | EP | disclosed |