Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.54 |
| ▸ | MAPT | P10636 | 6/20 | 0.54 |
| ▸ | LMNA | P02545 | 5/20 | 0.54 |
| ▸ | NPC1 | O15118 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | HTT | P42858 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | GAA | P10253 | 5/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | EGFR | P00533 | 2/20 | 0.41 |
| ▸ | FYN | P06241 | 2/20 | 0.41 |
| ▸ | MMP9 | P14780 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29975790 | 0.72 | — | — | |
| SCHEMBL431918 | 0.72 | — | — | |
| SCHEMBL11559449 | 0.71 | GAA (0.54) | SMN1; SMN2KDM4EMAPTNPC1MEN1 | |
| SCHEMBL9636666 | 0.71 | LMNA (0.48) | KDM4EMAPTLMNANPC1MEN1 | |
| SCHEMBL17372822 | 0.71 | MEN1 (0.40) | NPC1MEN1KMT2AALDH1A1GAA | |
| SCHEMBL7294187 | 0.71 | TSHR (0.41) | SMN1; SMN2KDM4EMAPTLMNANPC1 | |
| SCHEMBL304890 | 0.71 | MAPT (0.68) | SMN1; SMN2KDM4EMAPTLMNANPC1 | |
| SCHEMBL131175 | 0.71 | MAPT (1.00) | SMN1; SMN2KDM4EMAPTLMNANPC1 | |
| SCHEMBL574042 | 0.71 | MAPT (1.00) | SMN1; SMN2KDM4EMAPTLMNANPC1 | |
| SCHEMBL29354111 | 0.71 | MAPT (1.00) | SMN1; SMN2KDM4EMAPTLMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115340581-B | Synthesis method and application of o-phenol sulfenamide on-DNA compound | 深圳市小分子新药创新中心有限公司 | 2023-02-03 | — | — | CN | disclosed |
| CN-115340581-A | Synthesis method and application of o-phenol sulfenamide on-DNA compound | 深圳市小分子新药创新中心有限公司 | 2022-11-15 | — | — | CN | disclosed |