Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Ammonia Solution, Strong. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29255679 | 0.83 | RIPK1 (0.33) | — | |
| SCHEMBL1615586 | 0.80 | — | — | |
| SCHEMBL9636711 | 0.80 | — | — | |
| Acrylamide SCHEMBL11405460 | 0.73 | — | — | |
| Ammonia Solution, Strong SCHEMBL9636713 | 0.71 | — | — | |
| Amylene Hydrate SCHEMBL9716551 | 0.71 | ALDH1A1 (0.32) | — | |
| SCHEMBL28154935 | 0.70 | TSHR (0.44) | — | |
| SCHEMBL3624694 | 0.67 | RIPK1 (0.34) | — | |
| SCHEMBL1524596 | 0.67 | ELANE (0.33) | — | |
| SCHEMBL3624695 | 0.67 | RIPK1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5147635-A | For hair | CLAIROL INCORPORATED (US) | 1992-09-15 | — | — | US | disclosed |