Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 4/20 | 0.67 |
| ▸ | CHRNB4 | P30926 | 4/20 | 0.67 |
| ▸ | CHRNA3 | P32297 | 4/20 | 0.67 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.67 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.67 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.53 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7094723 | 0.80 | CHRNB2 (1.00) | CHRNB2CHRNB4CHRNA3CHRNA4CHRNA7 | |
| SCHEMBL14676930 | 0.77 | CHRNB2 (0.71) | CHRNB2CHRNB4CHRNA3CHRNA4CHRNA7 | |
| SCHEMBL6319408 | 0.76 | CHRNB2 (0.61) | CHRNB2CHRNB4CHRNA3CHRNA4CHRNA7 | |
| SCHEMBL19467972 | 0.75 | CHRNB2 (0.55) | CHRNB2CHRNB4CHRNA3CHRNA4CHRNA7 | |
| SCHEMBL19503230 | 0.75 | CHRNB2 (0.55) | CHRNB2CHRNB4CHRNA3CHRNA4CHRNA7 | |
| SCHEMBL31360681 | 0.74 | CHRNB2 (0.62) | CHRNB2CHRNB4CHRNA3CHRNA4CHRNA7 | |
| SCHEMBL3110491 | 0.74 | CHRNB2 (0.62) | CHRNB2CHRNB4CHRNA3CHRNA4CHRNA7 | |
| SCHEMBL9267508 | 0.74 | CHRNB2 (0.58) | CHRNB2CHRNB4CHRNA3CHRNA4CHRNA7 | |
| SCHEMBL14236778 | 0.74 | PLA2G1B (0.87) | CHRNB2CHRNB4CHRNA3CHRNA4CHRNA7 | |
| SCHEMBL10274486 | 0.73 | PLA2G1B (0.75) | CHRNB2CHRNB4CHRNA3CHRNA4CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5110933-A | Salts of 3-azabicyclo[3.3.1]nonanes as antiarrhythmic agents, and precursors thereof | BOARD OF REGENTS OF OKLAHOMA STATE UNIVERSITY (US) | 1992-05-05 | — | — | US | disclosed |
| US-5084572-A | Cardiovascular disorders | BOARD OF REGENTS OF OKLAHOMA STATE UNIVERSITY (US) | 1992-01-28 | — | — | US | disclosed |