Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 14/20 | 0.58 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.53 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9636920 | 1.00 | PPARG (0.58) | PPARGAGTR1AGTR2 | |
| Trifluoroacetic Acid SCHEMBL8392773 | 0.82 | PPARG (0.49) | PPARGAGTR1AGTR2 | |
| Trifluoroacetic Acid SCHEMBL8944557 | 0.82 | PPARG (0.49) | PPARGAGTR1AGTR2 | |
| SCHEMBL154 | 0.82 | AGTR1 (0.65) | AGTR1AGTR2 | |
| SCHEMBL152 | 0.82 | AGTR1 (0.65) | AGTR1AGTR2 | |
| SCHEMBL29394795 | 0.82 | AGTR1 (0.65) | AGTR1AGTR2 | |
| SCHEMBL9636909 | 0.81 | PPARG (0.63) | PPARGAGTR1AGTR2 | |
| SCHEMBL9853630 | 0.81 | PPARG (0.52) | PPARGAGTR1AGTR2 | |
| SCHEMBL9853634 | 0.81 | PPARG (0.52) | PPARGAGTR1AGTR2 | |
| SCHEMBL7054367 | 0.80 | AGTR1 (0.82) | PPARGAGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5137906-A | Treatment of central nervous system disorders with benzimidazole angiotensin-II receptor antagonists | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-08-11 | — | — | US | claimed |
| US-5137906-A | Treatment of central nervous system disorders with benzimidazole angiotensin-II receptor antagonists | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-08-11 | — | — | US | disclosed |
| US-4880804-A | HYPOTENSIVE AGENTS, CONGESTIVE HEART FAILURE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-11-14 | — | — | US | disclosed |