Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 14/20 | 0.63 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.58 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7054367 | 0.84 | AGTR1 (0.82) | PPARGAGTR1AGTR2 | |
| SCHEMBL153 | 0.83 | AGTR1 (0.71) | AGTR1AGTR2 | |
| SCHEMBL9682405 | 0.83 | AGTR1 (0.71) | AGTR1AGTR2 | |
| SCHEMBL9636907 | 0.81 | PPARG (0.58) | PPARGAGTR1AGTR2 | |
| SCHEMBL9636920 | 0.81 | PPARG (0.58) | PPARGAGTR1AGTR2 | |
| SCHEMBL137 | 0.81 | AGTR1 (0.54) | PPARGAGTR1AGTR2 | |
| SCHEMBL9682924 | 0.81 | AGTR1 (0.54) | PPARGAGTR1AGTR2 | |
| SCHEMBL8391692 | 0.79 | AGTR1 (0.83) | PPARGAGTR1AGTR2 | |
| SCHEMBL8396012 | 0.78 | PPARG (0.80) | PPARGAGTR1AGTR2 | |
| SCHEMBL8917758 | 0.78 | PPARG (0.72) | PPARGAGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5137906-A | Treatment of central nervous system disorders with benzimidazole angiotensin-II receptor antagonists | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-08-11 | — | — | US | claimed |
| US-5137906-A | Treatment of central nervous system disorders with benzimidazole angiotensin-II receptor antagonists | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-08-11 | — | — | US | disclosed |