Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | CYSLTR1 | Q9Y271 | 14/20 | 0.34 |
| ▸ | CYSLTR2 | Q9NS75 | 11/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9757265 | 0.85 | FFAR1 (0.37) | FFAR1AKR1B1CYSLTR1CYSLTR2 | |
| SCHEMBL9636824 | 0.78 | CYSLTR1 (0.45) | FFAR1AKR1B1CYSLTR1CYSLTR2ALOX5AP | |
| SCHEMBL9637032 | 0.72 | CYSLTR1 (0.46) | CYSLTR1CYSLTR2ALOX5AP | |
| SCHEMBL9636918 | 0.71 | CYSLTR2 (0.33) | CYSLTR1CYSLTR2ALOX5AP | |
| SCHEMBL9636819 | 0.71 | ALOX5AP (0.42) | FFAR1AKR1B1CYSLTR1CYSLTR2ALOX5AP | |
| SCHEMBL9760912 | 0.60 | CYSLTR1 (0.48) | FFAR1AKR1B1CYSLTR1CYSLTR2 | |
| SCHEMBL7751111 | 0.55 | CYSLTR1 (0.41) | FFAR1AKR1B1CYSLTR1CYSLTR2ALOX5AP | |
| SCHEMBL8649544 | 0.54 | FFAR1 (0.97) | FFAR1AKR1B1CYSLTR1CYSLTR2 | |
| SCHEMBL10545819 | 0.54 | CYSLTR1 (1.00) | FFAR1AKR1B1CYSLTR1CYSLTR2 | |
| SCHEMBL14021495 | 0.54 | CYSLTR1 (1.00) | FFAR1AKR1B1CYSLTR1CYSLTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5082849-A | Antiinflammatory agents or antiallergens | AVENTIS PHARMACEUTICALS INC. | 1992-01-21 | — | — | US | disclosed |
| EP-0434827-A1 | QUINOLINYL-BENZOPYRAN DERIVATIVES AS ANTAGONISTS OF LEUKOTRIENE D 4? | RORER INTERNATIONAL (HOLDINGS), INC. (US) | 1991-07-03 | — | — | EP | disclosed |
| WO-1991001123-A2 | QUINOLINYL-BENZOPYRAN DERIVATIVES AS ANTAGONISTS OF LEUKOTRIENE D¿4? | RORER INTERNATIONAL (OVERSEAS) INC. (US) | 1991-02-07 | — | — | WO | disclosed |
| US-4977162-A | Quinolinyl-chromone derivatives and use for treatment of hypersensitive ailments | RORER PHARMACEUTICAL CORPORATION (US) | 1990-12-11 | — | — | US | disclosed |