Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ARG1 | P05089 | 1/20 | 0.32 |
| ▸ | ARG2 | P78540 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9730898 | 1.00 | ARG1 (0.32) | ARG1ARG2CYP2D6SLC6A2SLC6A4 | |
| SCHEMBL7728931 | 0.81 | HCRTR2 (0.34) | — | |
| SCHEMBL8149234 | 0.81 | HCRTR2 (0.34) | — | |
| SCHEMBL8145398 | 0.79 | EPHX1 (0.37) | ARG1ARG2 | |
| SCHEMBL7379886 | 0.78 | HRH3 (0.46) | CYP2D6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL28175527 | 0.78 | ARG1 (0.38) | ARG1ARG2CYP2D6SLC6A2SLC6A4 | |
| SCHEMBL9637164 | 0.78 | — | — | |
| SCHEMBL5123125 | 0.78 | — | — | |
| SCHEMBL27190616 | 0.77 | HRH3 (0.38) | CYP2D6SLC6A2SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL28174609 | 0.77 | ARG1 (0.37) | ARG1ARG2CYP2D6SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0493506-A1 | CHIMERIC AMINO ACIDS AND PEPTIDES CONTAINING THESE ANALOGUES | GENENTECH, INC. (US) | 1992-07-08 | — | — | EP | disclosed |
| US-5120859-A | Anticoagulants | GENENTECH, INC. (US) | 1992-06-09 | — | — | US | disclosed |
| WO-1991004247-A1 | CHIMERIC AMINO ACIDS AND PEPTIDES CONTAINING THESE ANALOGUES | GENENTECH, INC. (US) | 1991-04-04 | — | — | WO | disclosed |