Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 3/20 | 0.48 |
| ▸ | MME | P08473 | 1/20 | 0.48 |
| ▸ | CPA1 | P15085 | 1/20 | 0.48 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.48 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.47 |
| ▸ | YARS1 | P54577 | 2/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 8/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9637011 | 1.00 | ACE (0.48) | ACEMMECPA1ACE2SLC7A5 | |
| SCHEMBL9637180 | 0.88 | CTSC (0.54) | ACEMMECPA1ACE2SLC7A5 | |
| SCHEMBL9637178 | 0.88 | CTSC (0.54) | ACEMMECPA1ACE2SLC7A5 | |
| SCHEMBL9636704 | 0.86 | ALOX15 (0.50) | ACEMMESLC7A5YARS1OPRK1 | |
| SCHEMBL9636699 | 0.86 | ALOX15 (0.50) | ACEMMESLC7A5YARS1OPRK1 | |
| SCHEMBL17713533 | 0.86 | ACE (0.52) | ACEMMECPA1ACE2OPRD1 | |
| SCHEMBL9638027 | 0.84 | CTSC (0.50) | ACEMMECPA1ACE2OPRD1 | |
| SCHEMBL9638023 | 0.84 | CTSC (0.50) | ACEMMECPA1ACE2OPRD1 | |
| SCHEMBL2193168 | 0.83 | ACE (0.50) | ACEMMECPA1ACE2OPRD1 | |
| SCHEMBL2183958 | 0.82 | SLC7A5 (0.53) | SLC7A5YARS1OPRD1OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0268678-B1 | NOVEL 5-FLUOROURIDINE COMPOUNDS AND PROCESS FOR THEIR PREPARATION | FUJI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1992-07-29 | — | — | EP | claimed |
| US-4892939-A | ANTITUMOR, ANTIVIRAL AND IMMUNOSUPRESSIVE AGENTS | FUJI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1990-01-09 | — | — | US | claimed |
| EP-0268678-A1 | NOVEL 5-FLUOROURIDINE COMPOUNDS AND PROCESS FOR THEIR PREPARATION | FUJI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1988-06-01 | — | — | EP | claimed |