Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 6/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.50 |
| ▸ | RECQL | P46063 | 3/20 | 0.50 |
| ▸ | USP2 | O75604 | 2/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.50 |
| ▸ | HTR2A | P28223 | 2/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.50 |
| ▸ | LCK | P06239 | 2/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.50 |
| ▸ | EGFR | P00533 | 1/20 | 0.50 |
| ▸ | FYN | P06241 | 1/20 | 0.50 |
| ▸ | YARS1 | P54577 | 2/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9636704 | 1.00 | ALOX15 (0.50) | ALOX15KDM4EHIF1AHSD17B10RECQL | |
| SCHEMBL9637011 | 0.86 | ACE (0.48) | SLC7A5YARS1OPRK1MMEACE | |
| SCHEMBL9637007 | 0.86 | ACE (0.48) | SLC7A5YARS1OPRK1MMEACE | |
| SCHEMBL9637180 | 0.83 | CTSC (0.54) | SLC7A5PTGS1CYP3A4MAPK1CYP1A2 | |
| SCHEMBL9637178 | 0.83 | CTSC (0.54) | SLC7A5PTGS1CYP3A4MAPK1CYP1A2 | |
| SCHEMBL11348530 | 0.82 | ALOX15 (0.58) | ALOX15KDM4EHIF1AHSD17B10RECQL | |
| SCHEMBL11348534 | 0.82 | ALOX15 (0.58) | ALOX15KDM4EHIF1AHSD17B10RECQL | |
| SCHEMBL9636710 | 0.81 | ALOX15 (0.50) | ALOX15KDM4EHIF1AHSD17B10RECQL | |
| SCHEMBL11858525 | 0.80 | CTSD (0.51) | ALOX15KDM4EHIF1AHSD17B10RECQL | |
| SCHEMBL11852549 | 0.79 | ALOX15 (0.48) | ALOX15KDM4EHIF1AHSD17B10RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0268678-B1 | NOVEL 5-FLUOROURIDINE COMPOUNDS AND PROCESS FOR THEIR PREPARATION | FUJI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1992-07-29 | — | — | EP | claimed |
| US-4892939-A | ANTITUMOR, ANTIVIRAL AND IMMUNOSUPRESSIVE AGENTS | FUJI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1990-01-09 | — | — | US | claimed |
| EP-0268678-A1 | NOVEL 5-FLUOROURIDINE COMPOUNDS AND PROCESS FOR THEIR PREPARATION | FUJI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1988-06-01 | — | — | EP | claimed |