Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | PLA2G4B | P0C869 | 3/20 | 0.47 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.47 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.46 |
| ▸ | CTRC | Q99895 | 1/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | RARB | P10826 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9637033 | 0.99 | TSHR (0.52) | TSHRMAOBTP53PLA2G4BNR4A1 | |
| SCHEMBL9636863 | 0.91 | MAOB (0.52) | TSHRMAOBPLA2G4BNR4A1NR4A2 | |
| SCHEMBL9637987 | 0.91 | MAOB (0.52) | TSHRMAOBPLA2G4BNR4A1NR4A2 | |
| SCHEMBL9799716 | 0.86 | ALDH1A1 (0.57) | TSHRMAOBNR4A1NR4A2NR4A3 | |
| SCHEMBL9346509 | 0.86 | ALDH1A1 (0.57) | TSHRMAOBNR4A1NR4A2NR4A3 | |
| SCHEMBL9638141 | 0.86 | MAOB (0.55) | MAOBTP53PLA2G4BNR4A1NR4A2 | |
| SCHEMBL9637978 | 0.86 | MAOB (0.55) | MAOBTP53PLA2G4BNR4A1NR4A2 | |
| SCHEMBL9489406 | 0.85 | RARB (0.60) | TSHRTP53PLA2G4BSMN1; SMN2RARB | |
| SCHEMBL9490043 | 0.85 | RARB (0.60) | TSHRTP53PLA2G4BSMN1; SMN2RARB | |
| SCHEMBL9489257 | 0.85 | RARB (0.60) | TSHRTP53PLA2G4BSMN1; SMN2RARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0301587-B1 | LIQUID CRYSTAL COMPOUNDS AND INTERMEDIATES THEREOF | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 1992-07-15 | — | — | EP | disclosed |
| US-5114615-A | Compounds for optical apparatus | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 1992-05-19 | — | — | US | disclosed |
| EP-0301587-A1 | Liquid crystal compounds and intermediates thereof | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 1989-02-01 | — | — | EP | disclosed |