SCHEMBL9637987

SCHEMBL9637987

CCCOCC(C)OC(=O)c1ccc(OCc2ccccc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.52
NR4A1 P22736 1/20 0.51
NR4A2 P43354 1/20 0.51
NR4A3 Q92570 1/20 0.51
HDAC3 O15379 1/20 0.50
HDAC1 Q13547 1/20 0.50
HDAC2 Q92769 1/20 0.50
NCOR2 Q9Y618 1/20 0.50
ADRB2 P07550 1/20 0.49
ADRB1 P08588 1/20 0.49
ADRB3 P13945 1/20 0.49
TSHR P16473 1/20 0.49
PARP10 Q53GL7 1/20 0.49
L3MBTL1 Q9Y468 2/20 0.48
LMNA P02545 1/20 0.48
RXRA P19793 2/20 0.48
RXRB P28702 2/20 0.48
SRD5A2 P31213 1/20 0.48
ALDH1A1 P00352 2/20 0.46
HTT P42858 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9636863 1.00 MAOB (0.52) MAOBNR4A1NR4A2NR4A3HDAC3
SCHEMBL9637033 0.92 TSHR (0.52) MAOBNR4A1NR4A2NR4A3HDAC3
SCHEMBL9637023 0.91 TSHR (0.51) MAOBNR4A1NR4A2NR4A3HDAC3
SCHEMBL9638141 0.90 MAOB (0.55) MAOBNR4A1NR4A2NR4A3HDAC3
SCHEMBL9637978 0.90 MAOB (0.55) MAOBNR4A1NR4A2NR4A3HDAC3
SCHEMBL9636860 0.88 MAOB (0.57) MAOBNR4A1NR4A2NR4A3ADRB2
SCHEMBL9636842 0.87 MAOB (0.51) MAOBNR4A1NR4A2NR4A3HDAC3
SCHEMBL11077363 0.85 LMNA (0.56) ADRB2ADRB1ADRB3TSHRLMNA
SCHEMBL9437156 0.81 MAOB (0.56) MAOBNR4A1NR4A2NR4A3HDAC3
SCHEMBL9490192 0.81 TSHR (0.62) ADRB2ADRB1ADRB3TSHRL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0301587-B1 LIQUID CRYSTAL COMPOUNDS AND INTERMEDIATES THEREOF WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 1992-07-15 EP disclosed
US-5114615-A Compounds for optical apparatus WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 1992-05-19 US disclosed
EP-0301587-A1 Liquid crystal compounds and intermediates thereof WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 1989-02-01 EP disclosed