Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | CASP6 | P55212 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28806661 | 0.85 | KDM4E (0.40) | KDM4EALDH1A1HPGDCYP2C9MEN1 | |
| SCHEMBL990076 | 0.85 | KDM4E (0.40) | KDM4EALDH1A1HPGDCYP2C9MEN1 | |
| SCHEMBL29366932 | 0.85 | KDM4E (0.40) | KDM4EALDH1A1HPGDCYP2C9MEN1 | |
| Hydrochloric Acid SCHEMBL6994200 | 0.84 | ALDH1A1 (0.39) | KDM4EALDH1A1HPGDCYP2C9MEN1 | |
| SCHEMBL3116614 | 0.82 | KDM4E (0.35) | KDM4EALDH1A1HPGDCYP2C9MEN1 | |
| SCHEMBL2971408 | 0.82 | ATM (0.41) | KDM4EALDH1A1HPGDCYP2C9MEN1 | |
| SCHEMBL4410965 | 0.82 | ATM (0.41) | KDM4EALDH1A1HPGDCYP2C9MEN1 | |
| SCHEMBL29696802 | 0.82 | ATM (0.41) | KDM4EALDH1A1HPGDCYP2C9MEN1 | |
| Hydrochloric Acid SCHEMBL19744196 | 0.81 | ATM (0.40) | KDM4EALDH1A1HPGDCYP2C9MEN1 | |
| SCHEMBL4972150 | 0.79 | KDM4E (0.33) | KDM4EALDH1A1HPGDNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102333779-B | Benzopyran and benzoxex PI3K inhibitor compounds and methods of use | GENENTECH, INC. (US) | 2015-12-09 | — | — | CN | disclosed |
| CN-102333779-A | Benzopyran and benzoxex PI3K inhibitor compounds and methods of use | GENENTECH INC | 2012-01-25 | — | — | CN | disclosed |
| US-5082849-A | Antiinflammatory agents or antiallergens | AVENTIS PHARMACEUTICALS INC. | 1992-01-21 | — | — | US | disclosed |
| EP-0434827-A1 | QUINOLINYL-BENZOPYRAN DERIVATIVES AS ANTAGONISTS OF LEUKOTRIENE D 4? | RORER INTERNATIONAL (HOLDINGS), INC. (US) | 1991-07-03 | — | — | EP | disclosed |
| WO-1991001123-A2 | QUINOLINYL-BENZOPYRAN DERIVATIVES AS ANTAGONISTS OF LEUKOTRIENE D¿4? | RORER INTERNATIONAL (OVERSEAS) INC. (US) | 1991-02-07 | — | — | WO | disclosed |
| US-4977162-A | Quinolinyl-chromone derivatives and use for treatment of hypersensitive ailments | RORER PHARMACEUTICAL CORPORATION (US) | 1990-12-11 | — | — | US | disclosed |