Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 1/20 | 0.49 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.46 |
| ▸ | GNPAT | O15228 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | THPO | P40225 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MME | P08473 | 3/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.40 |
| ▸ | BMP1 | P13497 | 1/20 | 0.39 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25774753 | 1.00 | ACE (0.49) | ACEFOLH1GNPATKDM4EMAPT | |
| SCHEMBL30038573 | 0.94 | MME (0.47) | ACEFOLH1GNPATKDM4EMAPT | |
| SCHEMBL29659587 | 0.90 | CA2 (0.51) | GNPATRECQLSMN1; SMN2MMECA2 | |
| SCHEMBL30797987 | 0.90 | CA2 (0.51) | GNPATRECQLSMN1; SMN2MMECA2 | |
| SCHEMBL929660 | 0.90 | ACE (0.55) | ACEFOLH1KDM4EMAPTTHRB | |
| SCHEMBL29682309 | 0.88 | FOLH1 (0.59) | ACEFOLH1GNPATKDM4EMAPT | |
| SCHEMBL358953 | 0.86 | KDM4E (0.57) | ACEFOLH1GNPATKDM4EMAPT | |
| SCHEMBL30051376 | 0.86 | KDM4E (0.57) | ACEFOLH1GNPATKDM4EMAPT | |
| SCHEMBL1983976 | 0.86 | KDM4E (0.57) | ACEFOLH1GNPATKDM4EMAPT | |
| SCHEMBL29051061 | 0.85 | MME (0.50) | GNPATMMECA2CA4SLC15A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11746114-B2 | Thermally sensitive protecting groups for cysteine for peptide cyclization and selective disulfide bond formation | UNIVERSITY OF WINDSOR (CA) | 2023-09-05 | — | — | US | disclosed |
| US-20220153749-A1 | Thermally Sensitive Protecting Groups for Cysteine for Peptide Cyclization and Selective Disulfide Bond Formation | UNIVERSITY OF WINDSOR (CA) | 2022-05-19 | — | — | US | disclosed |
| EP-0493506-A1 | CHIMERIC AMINO ACIDS AND PEPTIDES CONTAINING THESE ANALOGUES | GENENTECH, INC. (US) | 1992-07-08 | — | — | EP | disclosed |
| WO-1991004247-A1 | CHIMERIC AMINO ACIDS AND PEPTIDES CONTAINING THESE ANALOGUES | GENENTECH, INC. (US) | 1991-04-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220153749-A1 | Thermally Sensitive Protecting Groups for Cysteine for Peptide Cyclization and Selective Disulfide Bond Formation | PTMS, CTH, VIP | ACE 2119/4885FOLH1 555/4885GNPAT 2546/4885 |
| US-11746114-B2 | Thermally sensitive protecting groups for cysteine for peptide cyclization and selective disulfide bond formation | PTMS, CTH, VIP | ACE 2119/4885FOLH1 555/4885GNPAT 2546/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.