Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 3/20 | 0.52 |
| ▸ | CTSK | P43235 | 2/20 | 0.50 |
| ▸ | P2RX7 | Q99572 | 16/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28311763 | 0.85 | CTSS (0.55) | CTSSCTSKP2RX7LMNAGAA | |
| SCHEMBL108509 | 0.83 | CTSS (0.54) | CTSSCTSKP2RX7LMNAGAA | |
| SCHEMBL422330 | 0.83 | TSHR (0.57) | CTSSCTSKP2RX7LMNAGAA | |
| SCHEMBL16127683 | 0.83 | CTSS (0.57) | CTSSCTSKP2RX7LMNAGAA | |
| Hydrochloric Acid SCHEMBL2990630 | 0.81 | TSHR (0.55) | CTSSCTSKP2RX7LMNAGAA | |
| SCHEMBL29542921 | 0.81 | CTSS (0.57) | CTSSCTSKP2RX7LMNAGAA | |
| SCHEMBL3185133 | 0.81 | CTSS (0.52) | CTSSCTSKP2RX7LMNAGAA | |
| SCHEMBL324095 | 0.81 | CTSS (0.57) | CTSSCTSKP2RX7LMNAGAA | |
| SCHEMBL9524633 | 0.81 | CTSS (0.56) | CTSSCTSKP2RX7LMNAGAA | |
| SCHEMBL30562236 | 0.81 | CTSS (0.56) | CTSSCTSKP2RX7LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0365914-B1 | FLUORINE-CONTAINING ACETOPHENONES OPTIONALLY HALOGENATED IN THE CH3-GROUP, AND THEIR PREPARATION FROM FLUORINATED BENZONITRILES | BAYER AG (DE) | 1992-07-22 | — | — | EP | claimed |
| EP-0365914-A2 | Fluorine-containing acetophenones optionally halogenated in the CH3-group, and their preparation from fluorinated benzonitriles | BAYER AG (DE) | 1990-05-02 | — | — | EP | claimed |
| EP-0365914-A2 | Fluorine-containing acetophenones optionally halogenated in the CH3-group, and their preparation from fluorinated benzonitriles | BAYER AG (DE) | 1990-05-02 | — | — | EP | disclosed |
| EP-0365913-A2 | Substituted 2-aminothiazoles | BAYER AG (DE) | 1990-05-02 | — | — | EP | disclosed |