Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 3/20 | 0.54 |
| ▸ | CTSK | P43235 | 2/20 | 0.51 |
| ▸ | P2RX7 | Q99572 | 16/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28311763 | 0.86 | CTSS (0.55) | CTSSCTSKP2RX7LMNAGAA | |
| SCHEMBL422330 | 0.85 | TSHR (0.57) | CTSSCTSKP2RX7LMNAGAA | |
| SCHEMBL16127683 | 0.85 | CTSS (0.57) | CTSSCTSKP2RX7LMNAGAA | |
| SCHEMBL324095 | 0.83 | CTSS (0.57) | CTSSCTSKP2RX7LMNAGAA | |
| SCHEMBL3185133 | 0.83 | CTSS (0.52) | CTSSCTSKP2RX7LMNAGAA | |
| SCHEMBL9524633 | 0.83 | CTSS (0.56) | CTSSCTSKP2RX7LMNAGAA | |
| Hydrochloric Acid SCHEMBL2990630 | 0.83 | TSHR (0.55) | CTSSCTSKP2RX7LMNAGAA | |
| SCHEMBL9637140 | 0.83 | CTSS (0.52) | CTSSCTSKP2RX7LMNAGAA | |
| SCHEMBL29542921 | 0.83 | CTSS (0.57) | CTSSCTSKP2RX7LMNAGAA | |
| SCHEMBL30562236 | 0.83 | CTSS (0.56) | CTSSCTSKP2RX7LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 261 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107567439-A | The ketone derivatives of 2 homopiperazine, 1 base 4H, 1,3 benzothiazines 4 and the method for preparing the keto hydrochloride of 2 1,3 benzothiazine of (height) piperazine 4 | 洛桑联邦理工学院 | 2018-01-09 | — | — | CN | claimed |
| CN-107488146-A | ICD derivative and its preparation method and application | 中国科学院兰州化学物理研究所 | 2017-12-19 | — | — | CN | claimed |
| US-12590087-B2 | Inhibiting USP36 | VALO HEALTH, INC. (US) | 2026-03-31 | — | — | US | disclosed |
| US-12338243-B2 | P2X7 modulators | JANSSEN PHARMACEUTICA NV (BE) | 2025-06-24 | — | — | US | disclosed |
| US-12247027-B2 | P2X7 modulators | JANSSEN PHARMACEUTICA NV (BE) | 2025-03-11 | — | — | US | disclosed |
| CN-114222574-B | Inhibition of USP36 | 瓦洛健康股份有限公司 | 2024-12-17 | — | — | CN | disclosed |
| US-20240116930-A1 | P2X7 MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2024-04-11 | — | — | US | disclosed |
| US-11820770-B2 | P2X7 modulators | JANSSEN PHARMACEUTICA NV (BE) | 2023-11-21 | — | — | US | disclosed |
| US-11820770-B2 | P2X7 modulators | JANSSEN PHARMACEUTICA NV (BE) | 2023-11-21 | — | — | US | disclosed |
| US-11820770-B2 | P2X7 modulators | JANSSEN PHARMACEUTICA NV (BE) | 2023-11-21 | — | — | US | disclosed |
| CN-115894452-A | P2X7 receptor inhibitor | 四川大学 | 2023-04-04 | — | — | CN | disclosed |
| CN-1553828-A | Generation of ion exchanger media | ��Ĭɭ�����ѧ����˾ | 2004-12-08 | — | — | CN | disclosed |
| CN-1384743-A | Remedies or preventives for diseases in association with chemokines | TEIJIN LTD (JP) | 2002-12-11 | — | — | CN | disclosed |
| CN-1362954-A | Sulfamidohydroxamic acid metalloprotease inhibitor | SEARLE & CO (US) | 2002-08-07 | — | — | CN | disclosed |
| CN-1295677-A | Method and apparatus for accelerated orthokeratology | EASTA PHARMACEUTICALS INC (US) | 2001-05-16 | — | — | CN | disclosed |
| CN-1284165-A | Method and reagents for quantification of solid-phase reactions using fluorine NMR | AVENTISS PHARMACEUTICAL PRODUC (US) | 2001-02-14 | — | — | CN | disclosed |
| CN-1226803-A | Diphenyl heterocycles as potassium channel modulators | BRISTOL MYERS SQUIBB CO (US) | 1999-08-25 | — | — | CN | disclosed |
| CN-1043835-C | Bactericide for preventing and treating plant take-all disease | MONSANTO CO (US) | 1999-06-30 | — | — | CN | disclosed |
| CN-1100261-A | Herbicides | RHONE POULENC AGRICULTURE (GB) | 1995-03-22 | — | — | CN | disclosed |
| CN-1058880-A | The sulfoneoxime ester compound of tool Fungicidally active | DU PONT (US) | 1992-02-26 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12247027-B2 | P2X7 modulators | P2RX2, P2RX7, P2RY2 | CTSS 2569/4885CTSK 1661/4885P2RX7 2/4885 |
| US-12338243-B2 | P2X7 modulators | P2RX7, P2RX4, P2RX1 | CTSS 2298/4885CTSK 1472/4885P2RX7 1/4885 |
| US-11820770-B2 | P2X7 modulators | P2RX2, P2RX7, P2RY2 | CTSS 2569/4885CTSK 1661/4885P2RX7 2/4885 |
| US-20240116930-A1 | P2X7 MODULATORS | P2RX2, P2RX7, P2RY2 | CTSS 2569/4885CTSK 1661/4885P2RX7 2/4885 |
| US-12590087-B2 | Inhibiting USP36 | USP36, USP39, USP30 | CTSS 2261/4885CTSK 2409/4885P2RX7 4648/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.