Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | P2RY6 | Q15077 | 3/20 | 0.46 |
| ▸ | P2RY14 | Q15391 | 3/20 | 0.46 |
| ▸ | NT5E | P21589 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | HBB | P68871 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CTSB | P07858 | 3/20 | 0.42 |
| ▸ | CTSS | P25774 | 3/20 | 0.42 |
| ▸ | CTSL | P07711 | 2/20 | 0.42 |
| ▸ | TYMS | P04818 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9637176 | 1.00 | CYP3A4 (0.47) | CYP3A4CYP2D6CYP2C9CYP2C19RAB9A | |
| SCHEMBL9637218 | 0.96 | P2RY6 (0.44) | CYP3A4CYP2D6CYP2C9CYP2C19RAB9A | |
| SCHEMBL9637216 | 0.96 | P2RY6 (0.44) | CYP3A4CYP2D6CYP2C9CYP2C19RAB9A | |
| SCHEMBL11240778 | 0.93 | P2RY6 (0.48) | P2RY6P2RY14NT5ELMNATSHR | |
| SCHEMBL8670319 | 0.93 | P2RY6 (0.48) | P2RY6P2RY14NT5ELMNATSHR | |
| SCHEMBL9637000 | 0.93 | TYMS (0.44) | CYP3A4CYP2D6CYP2C9CYP2C19RAB9A | |
| SCHEMBL9636996 | 0.93 | TYMS (0.44) | CYP3A4CYP2D6CYP2C9CYP2C19RAB9A | |
| SCHEMBL9638053 | 0.91 | REN (0.44) | CYP3A4CYP2D6CYP2C9CYP2C19RAB9A | |
| SCHEMBL9638269 | 0.91 | P2RY6 (0.50) | P2RY6P2RY14NT5ELMNATSHR | |
| SCHEMBL9638270 | 0.91 | P2RY6 (0.50) | P2RY6P2RY14NT5ELMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0268678-B1 | NOVEL 5-FLUOROURIDINE COMPOUNDS AND PROCESS FOR THEIR PREPARATION | FUJI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1992-07-29 | — | — | EP | disclosed |
| US-4892939-A | ANTITUMOR, ANTIVIRAL AND IMMUNOSUPRESSIVE AGENTS | FUJI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1990-01-09 | — | — | US | disclosed |
| EP-0268678-A1 | NOVEL 5-FLUOROURIDINE COMPOUNDS AND PROCESS FOR THEIR PREPARATION | FUJI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1988-06-01 | — | — | EP | disclosed |