Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 1/20 | 0.44 |
| ▸ | CTSB | P07858 | 6/20 | 0.43 |
| ▸ | CTSK | P43235 | 6/20 | 0.43 |
| ▸ | TYMS | P04818 | 1/20 | 0.43 |
| ▸ | P2RY6 | Q15077 | 2/20 | 0.40 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.40 |
| ▸ | NT5E | P21589 | 1/20 | 0.40 |
| ▸ | MME | P08473 | 1/20 | 0.40 |
| ▸ | ECE1 | P42892 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9637000 | 0.98 | TYMS (0.44) | RENCTSBCTSKTYMSP2RY6 | |
| SCHEMBL9636996 | 0.98 | TYMS (0.44) | RENCTSBCTSKTYMSP2RY6 | |
| SCHEMBL9637218 | 0.94 | P2RY6 (0.44) | CTSBCTSKTYMSP2RY6P2RY14 | |
| SCHEMBL9637216 | 0.94 | P2RY6 (0.44) | CTSBCTSKTYMSP2RY6P2RY14 | |
| SCHEMBL10694865 | 0.93 | TDP1 (0.41) | RENCTSBCTSKTYMS | |
| SCHEMBL9637913 | 0.93 | TDP1 (0.41) | RENCTSBCTSKTYMS | |
| SCHEMBL9637176 | 0.91 | CYP3A4 (0.47) | CTSBCTSKTYMSP2RY6P2RY14 | |
| SCHEMBL9637173 | 0.91 | CYP3A4 (0.47) | CTSBCTSKTYMSP2RY6P2RY14 | |
| SCHEMBL9636927 | 0.91 | TDP1 (0.42) | P2RY6P2RY14NT5E | |
| SCHEMBL10332220 | 0.89 | TYMS (0.44) | TYMSP2RY6P2RY14NT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0268678-B1 | NOVEL 5-FLUOROURIDINE COMPOUNDS AND PROCESS FOR THEIR PREPARATION | FUJI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1992-07-29 | — | — | EP | disclosed |
| US-4892939-A | ANTITUMOR, ANTIVIRAL AND IMMUNOSUPRESSIVE AGENTS | FUJI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1990-01-09 | — | — | US | disclosed |
| EP-0268678-A1 | NOVEL 5-FLUOROURIDINE COMPOUNDS AND PROCESS FOR THEIR PREPARATION | FUJI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1988-06-01 | — | — | EP | disclosed |