Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | MTOR | P42345 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | HTR2C | P28335 | 2/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.45 |
| ▸ | KCNK2 | O95069 | 2/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.45 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL9637431 | 0.78 | SLC6A4 (0.66) | SLC7A5SLC6A4MEN1KMT2ALMNA | |
| SCHEMBL3752 | 0.76 | SLC6A2 (0.37) | SLC6A4SLC6A2CHRM1 | |
| SCHEMBL3942629 | 0.74 | SLC7A5 (0.53) | SLC7A5SLC6A4MEN1KMT2ALMNA | |
| SCHEMBL16347642 | 0.69 | SLC6A9 (0.47) | SLC6A4MEN1KMT2ALMNASLC6A2 | |
| Fluoxetine SCHEMBL9715830 | 0.69 | SLC6A4 (0.86) | SLC7A5SLC6A4MEN1KMT2ALMNA | |
| SCHEMBL6006291 | 0.68 | SLC7A5 (0.68) | SLC7A5SLC6A4MEN1KMT2ALMNA | |
| Hydrochloric Acid SCHEMBL9500934 | 0.66 | SLC6A4 (0.74) | SLC7A5SLC6A4MEN1KMT2ALMNA | |
| SCHEMBL9411503 | 0.65 | SLC6A2 (0.33) | SLC6A4MEN1KMT2ALMNASLC6A2 | |
| SCHEMBL4739538 | 0.65 | SLC6A9 (0.52) | SLC6A4MEN1KMT2ALMNASLC6A2 | |
| SCHEMBL17267554 | 0.65 | SLC7A5 (1.00) | SLC7A5SLC6A4MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0336753-B1 | IMPROVEMENTS IN OR RELATING TO PROPANAMINE DERIVATIVES | ELI LILLY AND COMPANY (US) | 1992-07-08 | — | — | EP | disclosed |
| EP-0336753-A1 | Improvements in or relating to propanamine derivatives | ELI LILLY AND COMPANY (US) | 1989-10-11 | — | — | EP | disclosed |