SCHEMBL16347642

SCHEMBL16347642

CNC(CC(Oc1ccc(C)cc1)c1ccccc1)OC(=O)C(=O)OC(CC(Oc1ccc(C)cc1)c1ccccc1)NC

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A9 P48067 3/20 0.47
SLC6A4 P31645 8/20 0.43
PPARG P37231 1/20 0.40
PPARA Q07869 1/20 0.40
ALDH1A1 P00352 2/20 0.40
HPGD P15428 1/20 0.40
HTR1A P08908 1/20 0.40
NPC1 O15118 2/20 0.39
CYP2D6 P10635 2/20 0.39
CYP2C19 P33261 2/20 0.39
MTOR P42345 2/20 0.39
RAB9A P51151 2/20 0.39
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
LMNA P02545 2/20 0.39
KDM4E B2RXH2 1/20 0.39
TP53 P04637 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2C9 P11712 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4941291 0.92 SLC6A4 (0.47) SLC6A9SLC6A4PPARGPPARAALDH1A1
SCHEMBL7310728 0.82 SLC6A9 (0.49) SLC6A9SLC6A4PPARGPPARAALDH1A1
SCHEMBL2526 0.81 HTT (0.44) SLC6A4ALDH1A1RAB9AKDM4ETSHR
SCHEMBL10155 0.81 TRPM8 (0.42) HPGDRAB9ATP53SLC6A2
SCHEMBL5869614 0.80 MRGPRX4 (0.41) SLC6A4MEN1KMT2A
SCHEMBL5869414 0.80 MRGPRX4 (0.41) SLC6A4MEN1KMT2A
SCHEMBL5027210 0.77 SLC6A9 (0.47) SLC6A9SLC6A4PPARGPPARAALDH1A1
SCHEMBL8011874 0.76 NOS2 (0.47) SLC6A4ALDH1A1HPGDNPC1CYP2D6
SCHEMBL4739538 0.75 SLC6A9 (0.52) SLC6A9SLC6A4ALDH1A1HPGDHTR1A
SCHEMBL4936018 0.75 CYP1A2 (0.43) SLC6A9SLC6A4PPARGPPARAHTR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015001565-A2 \"AN IMPROVED PROCESS FOR THE PREPARATION OF 3-ARYLOXY-3- PHENYLPROPYLAMINE AND SALT THEREOF\ ZCL CHEMICALS LIMITED (IN) 2015-01-08 WO disclosed