SCHEMBL9637459

SCHEMBL9637459

COc1ccc(N)c(S(=O)(=O)O)c1.Nc1ccc(S(=O)(=O)O)cc1S(=O)(=O)O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTDSP1 Q9GZU7 1/20 0.47
ALDH1A1 P00352 6/20 0.45
HSD17B10 Q99714 3/20 0.45
CYP2C9 P11712 1/20 0.44
CYP2C19 P33261 1/20 0.44
CASP6 P55212 1/20 0.44
TDP1 Q9NUW8 2/20 0.42
CYP3A4 P08684 1/20 0.42
TSHR P16473 1/20 0.42
PKM P14618 3/20 0.42
GAA P10253 2/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
KDM4E B2RXH2 1/20 0.41
MAPT P10636 1/20 0.41
THRB P10828 1/20 0.41
RECQL P46063 1/20 0.41
BLM P54132 1/20 0.41
MCL1 Q07820 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31532623 0.92 CTDSP1 (0.52) CTDSP1ALDH1A1TDP1CYP3A4PKM
SCHEMBL158764 0.92 CTDSP1 (0.52) CTDSP1ALDH1A1TDP1CYP3A4PKM
Nitrogen SCHEMBL28911658 0.89 CTDSP1 (0.50) CTDSP1ALDH1A1HSD17B10TDP1CYP3A4
SCHEMBL153646 0.85 ALDH1A1 (0.59) CTDSP1ALDH1A1HSD17B10CYP2C9CYP2C19
SCHEMBL142003 0.85 ALDH1A1 (0.59) CTDSP1ALDH1A1HSD17B10CYP2C9CYP2C19
SCHEMBL9401917 0.84 CTDSP1 (0.47) CTDSP1ALDH1A1CASP6TDP1CYP3A4
SCHEMBL142001 0.83 ALDH1A1 (0.57) CTDSP1ALDH1A1HSD17B10CYP2C9CYP2C19
Hydrochloric Acid SCHEMBL28203178 0.83 ALDH1A1 (0.57) CTDSP1ALDH1A1HSD17B10CYP2C9CYP2C19
SCHEMBL7064778 0.83 ALDH1A1 (0.57) CTDSP1ALDH1A1HSD17B10CYP2C9CYP2C19
SCHEMBL9637465 0.80 TIMP3 (0.44) ALDH1A1HSD17B10PKMGAAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5175261-A Useful for coloring cellulose materials, animal furs or leather IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1992-12-29 US disclosed