Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.36 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.33 |
| ▸ | ERN1 | O75460 | 2/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12492138 | 0.87 | CYP1A2 (0.43) | TLR2BACE1BIRC5HDAC1HDAC2 | |
| SCHEMBL2621781 | 0.79 | BACE1 (0.38) | BACE1MALT1BIRC5MEN1KMT2A | |
| SCHEMBL18562139 | 0.79 | CYP1A2 (0.40) | BACE1MALT1BIRC5MEN1KMT2A | |
| SCHEMBL9302 | 0.79 | ALDH1A1 (0.41) | BACE1MALT1BIRC5HDAC1HDAC2 | |
| SCHEMBL273345 | 0.77 | PDGFRB (0.51) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL12850737 | 0.77 | MALT1 (0.38) | BACE1MALT1BIRC5MEN1KMT2A | |
| SCHEMBL2621784 | 0.76 | CCR5 (0.39) | BACE1MALT1HDAC1HDAC2HDAC3 | |
| SCHEMBL20528292 | 0.76 | BACE1 (0.47) | BACE1MALT1BIRC5CYP2A6MEN1 | |
| SCHEMBL2621783 | 0.75 | HTT (0.39) | BACE1MALT1CYP2A6APPPIM1 | |
| SCHEMBL12277481 | 0.75 | HTT (0.41) | BIRC5CYP2A6HDAC8MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4519384-A1 | PHOTOACTIVATABLE COMPOUNDS AND USES THEREOF | Promega Corporation (US) | 2025-03-12 | — | — | EP | disclosed |
| WO-2023215497-A1 | PHOTOACTIVATABLE COMPOUNDS AND USES THEREOF | PROMEGA CORPORATION (US) | 2023-11-09 | — | — | WO | disclosed |
| EP-2504315-A1 | AMINO HETEROARYL COMPOUNDS AS BETA-SECRETASE MODULATORS AND METHODS OF USE | Amgen Inc. (US) | 2012-10-03 | — | — | EP | disclosed |
| WO-2011063233-A1 | AMINO HETEROARYL COMPOUNDS AS BETA-SECRETASE MODULATORS AND METHODS OF USE | AMGEN INC. (US) | 2011-05-26 | — | — | WO | disclosed |